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Mashup Score: 5Genome-wide meta-analysis implicates variation affecting mast cell biology in urticaria - 2 month(s) ago
Urticaria is characterized by inappropriate mast cell degranulation leading to the development of wheals and/or angioedema. Twin and family studies in…
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Mashup Score: 7Single-cell transcriptomics reveals granzyme K–expressing cytotoxic Tfh cells in tertiary lymphoid structures in IgG4-RD - 2 month(s) ago
Germinal center (GC) responses controlled by T follicular helper (Tfh) and T follicular regulatory (Tfr) cells are crucial for the generation of high-…
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Mashup Score: 12Immune responses to SARS-CoV-2 mRNA vaccination in people with idiopathic CD4 lymphopenia - 2 month(s) ago
The immunogenicity of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) mRNA vaccines is variable in individuals with different inborn erro…
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Mashup Score: 17Chemokine CCL19 promotes type 2 T cell differentiation and allergic airway inflammation - 2 month(s) ago
Allergic asthma is driven largely by allergen-specific type 2 T helper (Th2) cells, which develop in regional lymph nodes upon the interaction of naïv…
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Mashup Score: 10Remibrutinib demonstrates favorable safety profile and sustained efficacy in chronic spontaneous urticaria over 52 weeks - 2 month(s) ago
Remibrutinib (LOU064), an oral, highly selective Bruton tyrosine kinase inhibitor, offers fast disease control in patients with chronic spontaneous ur…
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Mashup Score: 24
In individuals without symptomatic food allergy, food-specific IgE is considered clinically irrelevant. However, recent studies have suggested that ga…
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Mashup Score: 10Revised Swedish infant feeding guidelines are associated with earlier introduction of allergenic foods - 3 month(s) ago
Randomized controlled trials have demonstrated that early introduction of allergenic foods, such as peanut and egg, can reduce food allergy in high-ri…
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Mashup Score: 14IgE directly affects eosinophil migration in chronic rhinosinusitis with nasal polyps through CCR3 and predicts the efficacy of omalizumab - 3 month(s) ago
Whether IgE affects eosinophil migration in chronic rhinosinusitis with nasal polyps (CRSwNP) remains largely unclear. Moreover, our understanding of …
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Mashup Score: 3Asthma morbidity measures across Black ethnic subgroups - 3 month(s) ago
Black adults are disproportionately affected by asthma and are often considered a homogeneous group in research studies despite cultural and ancestral…
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Mashup Score: 2Untargeted metabolomic profiling in children identifies novel pathways in asthma and atopy - 3 month(s) ago
Asthma and other atopic disorders can present with varying clinical phenotypes marked by differential metabolomic manifestations and enriched biologic…
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Urticaria is characterized by aberrant cutaneous mast cell degranulation, wheals, and/or swelling. A Brief report’s data from 3 European cohorts identifies common genetic variation influencing the risk of developing urticaria at 6 genomic loci. Read on. https://t.co/Hmk3o1HRAK