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Mashup Score: 0Function of cell adhesion molecules in differentiation of ray sensory neurons in C. elegans - 11 month(s) ago
Abstract. For proper functioning of the nervous system, it is crucial that neurons find their appropriate partners and build the correct neural connection patte
Source: OUP AcademicCategories: Genetics, Latest HeadlinesTweet
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Mashup Score: 0Comparative analysis of the testes from wild-type and Alkbh5-knockout mice using single-cell RNA sequencing - 11 month(s) ago
Abstract. The RNA demethylase ALKBH5 is regarded as the “eraser” in N6-methyladenosine modification. ALKBH5 deficiency causes male infertility in mice; however,
Source: OUP AcademicCategories: Genetics, Latest HeadlinesTweet-
Hong et al. provide the first single-cell RNA sequencing profile of the testes of mice lacking the N6-methyladenosine RNA eraser ALKBH5, highlighting its role in germ cell development and spermatogenesis. #G3Journal | https://t.co/DLD72hjgKI https://t.co/Kpv5UY8Wl4
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Mashup Score: 0
Abstract. Understanding the targets of selection associated with changes in behavioral traits represents an important challenge of current evolutionary research
Source: OUP AcademicCategories: Genetics, Latest HeadlinesTweet-
Espíndola-Hernández et al. search for signals of accelerated rates of evolution associated with a diurnal lifestyle in owls using a genome-wide comparative approach and identify owl-specific noncoding elements as potential candidates. #G3Journal | https://t.co/qGDvLS1viN https://t.co/jgGb696Z17
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Mashup Score: 0Caenorhabditis elegans innexin INX-20 regulates nociceptive behavioral sensitivity - 12 month(s) ago
Abstract. Organisms rely on chemical cues in their environment to indicate the presence or absence of food, reproductive partners, predators, or other harmful s
Source: OUP AcademicCategories: Genetics, Latest HeadlinesTweet-
Chaubey et al. report that #Celegans lacking the gap junction component INX-20 are hypersensitive in their behavioral response to both soluble and volatile chemical stimuli that signal through G protein-coupled receptor pathways in ASH neurons. #GENETICS | https://t.co/rU5pwzW4LJ https://t.co/hzlN9nY35D
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Mashup Score: 0
Exciting opportunity in Toronto, ON for The Hospital for Sick Children as a Post-Doctoral Researc…
Source: GSA Job BoardCategories: Genetics, Latest HeadlinesTweet-
From the GSA Job Board: 📌 Postdoctoral fellow to apply, develop and improve technologies for generating mouse models of human disease at The Hospital for Sick Children. https://t.co/4q0M5YQwVI | #GeneticsJobs • #PostdocJobs
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Mashup Score: 0Functional analysis of 110 phosphorylation sites on the circadian clock protein FRQ identifies clusters determining period length and temperature compensation - 12 month(s) ago
Abstract. In the negative feedback loop driving the Neurospora circadian oscillator, the negative element, FREQUENCY (FRQ), inhibits its own expression by promo
Source: OUP AcademicCategories: Genetics, Latest HeadlinesTweet-
Wang et al. systematically investigate the role in period determination of all 110 reported phosphorylation sites on the circadian clock protein FRQ, and identify clusters determining period length and temperature compensation. #G3Journal | https://t.co/zJ9wYJRWdI https://t.co/EhgEGJZU38
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Mashup Score: 0Statistical analysis of spatially resolved transcriptomic data by incorporating multiomics auxiliary information - 12 month(s) ago
Abstract. Effective control of false discovery rate is key for multiplicity problems. Here, we consider incorporating informative covariates from external datas
Source: OUP AcademicCategories: Genetics, Latest HeadlinesTweet-
Effective control of false discovery rate is key for multiplicity problems. Here, Li et al. incorporate informative covariates from external datasets to boost statistical power while maintaining false discovery rate control. #GENETICS | https://t.co/HX6jrEbifB https://t.co/gmTAcboIy1
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Mashup Score: 3Conserved function of Drosophila Fancd2 monoubiquitination in response to double-strand DNA breaks - 12 month(s) ago
Abstract. Fanconi anemia genes play key roles in metazoan DNA damage responses, and human FA mutations cause numerous disease phenotypes. In human cells, activa
Source: OUP AcademicCategories: Genetics, Latest HeadlinesTweet-
Clay et al. employ several novel and recently developed #Drosophila tools to study conserved roles of fancd2 — a gene associated with the autosomal recessive condition Fanconi anemia in humans — in response to dsDNA breaks. #G3Journal | https://t.co/wd2LqrfMIm https://t.co/0kRNvGiVqo
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Mashup Score: 0Local fitness and epistatic effects lead to distinct patterns of linkage disequilibrium in protein-coding genes - 12 month(s) ago
Abstract. Selected mutations interfere and interact with evolutionary processes at nearby loci, distorting allele frequency trajectories and creating correlatio
Source: OUP AcademicCategories: Genetics, Latest HeadlinesTweet-
Aaron Ragsdale develops a numerical approach to compute the expected two-locus sampling distribution under diploid selection with arbitrary epistasis and dominance, recombination, and variable population size. #GENETICS | https://t.co/EpEHU8ot6y https://t.co/0Zxj3DT88k
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Mashup Score: 2Variation in mutational (co)variances - 12 month(s) ago
Abstract. Because of pleiotropy, mutations affect the expression and inheritance of multiple traits and, together with selection, are expected to shape standing
Source: OUP AcademicCategories: Genetics, Latest HeadlinesTweet-
Mallard et al. use six independent traits of locomotion behavior as a model in #Celegans to characterize the M matrix in two genotypes and compare it with the G matrix of a lab-adapted population with standing genetic variation. #G3Journal | https://t.co/SRLQakq4lO https://t.co/sJJnWf8BXP
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Sakai et al. analyze the effects of mutations in cell adhesion molecules genes on the morphology and synapses of sensory neurons in #Celegans by examining their effect on axon trajectory and localization of pre-synaptic components. #G3Journal | https://t.co/U4CoaiFFJ1 https://t.co/S5bJK8J7eR