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Mashup Score: 0Real-world EGFR testing practices for non-small-cell lung cancer by thoracic pathology laboratories across Europe - 8 month(s) ago
Testing for epidermal growth factor receptor (EGFR) mutations is an essential recommendation in guidelines for metastatic non-squamous non-small-cell lung cancer, and is considered mandatory in European countries. However, in practice, challenges are often faced when carrying out routine biomarker testing, including access to testing, inadequate tissue samples and long turnaround times (TATs).
Source: www.esmoopen.comCategories: Latest Headlines, Oncologists1Tweet
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Mashup Score: 0Report: High Arsenic Levels in Many Texans' Drinking Water - 8 month(s) ago
Tens of thousands of Texans live in places where the drinking water contains toxic levels of arsenic — a known carcinogen — and the state isn’t doing enough to discourage them from consuming it, acco…
Source: www.texastribune.orgCategories: Latest Headlines, Oncologists1Tweet
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Mashup Score: 0Treatment at Twilight: An analysis of therapy patterns and outcomes in adults 80 years and older with advanced or metastatic non-small cell lung cancer - 8 month(s) ago
The aim of this study is to assess treatment patterns, survival outcomes, and factors influencing systemic treatment decisions in adults ≥80 years with non-small cell lung cancer (NSCLC).
Source: www.jtocrr.orgCategories: Latest Headlines, Oncologists1Tweet
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Mashup Score: 0Global trends in incidence, death, burden and risk factors of early-onset cancer from 1990 to 2019 - 8 month(s) ago
Objective This study aimed to explore the global burden of early-onset cancer based on the Global Burden of Disease (GBD) 2019 study for 29 cancers worldwid. Methods and analysis Incidence, deaths, disability-adjusted life years (DALYs) and risk factors for 29 early-onset cancer groups were obtained from GBD. Results Global incidence of early-onset cancer increased by 79.1% and the number of early-onset cancer deaths increased by 27.7% between 1990 and 2019. Early-onset breast, tracheal, bronchus and lung, stomach and colorectal cancers showed the highest mortality and DALYs in 2019. Globally, the incidence rates of early-onset nasopharyngeal and prostate cancer showed the fastest increasing trend, whereas early-onset liver cancer showed the sharpest decrease. Early-onset colorectal cancers had high DALYs within the top five ranking for both men and women. High-middle and middle Sociodemographic Index (SDI) regions had the highest burden of early-onset cancer. The morbidity of early-on
Source: bmjoncology.bmj.comCategories: Hem/Oncs, Latest HeadlinesTweet
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Mashup Score: 1Opinion | The shrinking number of primary care physicians is reaching a tipping point - 8 month(s) ago
The dispirited feeling that drives doctors away from primary care involves more than money. It’s lack of respect. Crammed patient rosters. Insufficient support.
Source: www.washingtonpost.comCategories: Latest Headlines, Oncologists1Tweet
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Mashup Score: 4
Europe is facing record heat and floods, intensified by climate change, just after it endured historic fires. More than 30 inches of rain could fall in Greece.
Source: www.washingtonpost.comCategories: Latest Headlines, Oncologists1Tweet
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Mashup Score: 1
A phase 2 study of stereotactic body radiation therapy and in situoncolytic virus therapy in metastatic non-small cell lung cancer (mNSCLC) followed by Pembrolizumab (STOMP) was designed to explore the dual approach in enhancing single pembrolizumab with ADV/HSV-tk plus valacyclovir gene therapy and stereotactic radiotherapy (SBRT) in mNSCLC.
Source: www.redjournal.orgCategories: Latest Headlines, Oncologists1Tweet
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Mashup Score: 1Save the Planet, Put Down that Hamburger - 10 month(s) ago
Researchers examined the diets of 55,500 people and found that vegans are responsible for 75 percent fewer greenhouse gases than meat-eaters.
Source: www.nytimes.comCategories: Latest Headlines, Oncologists1Tweet
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Mashup Score: 2U.S. workers have few legal protections from extreme heat - 10 month(s) ago
At least 436 people died of work-related environmental heat exposure from 2011-2021.
Source: www.axios.comCategories: Hem/Oncs, Latest HeadlinesTweet
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Mashup Score: 1Burden of serious harms from diagnostic error in the USA - 10 month(s) ago
Background Diagnostic errors cause substantial preventable harms worldwide, but rigorous estimates for total burden are lacking. We previously estimated diagnostic error and serious harm rates for key dangerous diseases in major disease categories and validated plausible ranges using clinical experts. Objective We sought to estimate the annual US burden of serious misdiagnosis-related harms (permanent morbidity, mortality) by combining prior results with rigorous estimates of disease incidence. Methods Cross-sectional analysis of US-based nationally representative observational data. We estimated annual incident vascular events and infections from 21.5 million (M) sampled US hospital discharges (2012–2014). Annual new cancers were taken from US-based registries (2014). Years were selected for coding consistency with prior literature. Disease-specific incidences for 15 major vascular events, infections and cancers (‘Big Three’ categories) were multiplied by literature-based rates to der
Source: qualitysafety.bmj.comCategories: Hem/Oncs, Latest HeadlinesTweet
Sobering results. "Many laboratories across Europe still favour single-test sequencing as a primary method of EGFR mutation identification". We need standardization of NGS panel testing so the most patients can potentially receive the right therapy #LCSM https://t.co/7MCZqCVjBU