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    More than 35 amyloid precursor proteins have been identified and many have tropism for the kidney. Renal amyloidosis is most commonly seen in AL and AA amyloidosis and the main clinical manifestations are proteinuria and progressive renal dysfunction. On renal pathology, hallmark findings of amyloidosis include Congo red positivity with apple-green birefringence and randomly arranged fibrils…

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    • "Renal #Amyloidosis: Presentation, Diagnosis, & Management" By Drs. Reena Gurung & Tingting Li @Ting2li @WUNephrology -Subtypes with renal involvement -Proteinuria & renal dysfunction -Supportive management 🧂💊 -HD/Transplant considerations 🏥 https://t.co/iUnHOx1inI 8/11 https://t.co/7o7v5KFaxQ

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    Transthyretin amyloidosis (ATTR) is an under-recognized cause of cardiomyopathy and neuropathy. Until recently, there were limited therapeutic options for ATTR. However, new therapeutics including tafamidis, patisiran, and inotersen increase both quality and length of life of patients with ATTR. This review details the chronological development of ATTR therapies through landmark clinical trials….

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    • "Developing Therapy for ATTR #Amyloidosis" by Drs. Courtney Campbell (me!), Katie Zhang, Dan Lenihan, & Ron Witteles @Ron_Witteles -Available therapies for ATTR 💊 -Data✍️ for stabilizers & silencers -Ongoing clinical trials for ATTR ❤️🧠 https://t.co/f9PtV5fglJ 9/11 https://t.co/DTuJOXSPgr

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    Light chain amyloidosis (AL) is a potentially fatal disease of monoclonal plasma cells which leads to accumulation of light chain amyloid fibrils, organ damage and the manifestations of clinical disease. Meanwhile, COVID-19 is a disease caused by infection with the SARS-CoV-2 virus, with the potential to cause severe systemic illness and death. There is significant overlap in the demographics and…

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    • "COVID-19 & Light Chain #Amyloidosis: Adding Insult to Injury" by Drs. Zachary Crees & Keith Stockerl-Goldstein @CyclingDoctor -Optimize Treatment 💊 -Mitigate Risk 😷📞 -Vaccination Considerations💉 https://t.co/yZ8p41Iu0h 10/11 https://t.co/6Q4WhzN55L

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    AL amyloidosis is challenging to diagnose and it should be considered a cardiac emergency. There has been a great deal of advances in the treatment of AL amyloidosis from initial descriptions of melphalan therapy until the recent approval of the first AL amyloidosis specific drug (daratumumab). Comprehension of the pathophysiology and biology of AL amyloidosis is key to understand the major…

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    • "Future Developments 🔬 in Light Chain #Amyloidosis Management" by Drs. Mario Rodriguez @wustlcardfellow, Dan Lenihan, & Giampaolo Merlini @gmerlini -Alkylators -Monoclonal abs -Proteosome inhibitors -Immunomodulators -Protein stabilizers https://t.co/ogZErs0hZm 11/11 Fin! https://t.co/HsZojXg68D

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    Are you interested in finding a Cardio-Oncology training program or fellowship? Browse our current list to see what’s available.

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    • If you are a #ACCFIT considering additional training in cardio-oncology, learn about fellowships here: https://t.co/Pp8wheouFG Invaluable clinical experience PLUS you can incorporate advanced training in basic or clinical research, cardiac imaging, or whatever fits your goals! https://t.co/fSjvmc2AWY

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    Did you know that 47% of American adults – nearly 1 in 2 – have high blood pressure? Many people don’t even know they have high blood pressure (also called hypertension). That’s because there are often no warning signs. But having high blood pressure makes a stroke or heart attack much more likely.Why? High blood pressure is the force of your blood moving against the walls of…

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    • Masterclass in management of #Hypertension in #CardioOnc at @ACCinTouch's CV Care of Onc Patient. The fantastic @KerrySkurka shares practical pearls to ensure accurate BP measurements. Also check out: https://t.co/49sVCWjd6Z #MedTwitter #CardioTwitter https://t.co/678ENPy5QR

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    Access until April 25, 2021 Learn how to access the site, use the live chat features, and claim credits. Join Course Directors Ana Barac, MD, PhD, FACC and Bonnie Ky, MD, MSCE, FACC for Advancing the Cardiovascular Care of the Oncology Patient Virtual! Register and gain access to: Live educational sessions with real-time discussion opportunities…

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    • Excited for @ACCinTouch's Virtual #CardioOnc ♥️ Conference w Q&A Fri 2/5 & talks Sat 2/6! Last year's conference introduced me to the amazing #CardioOnc🥰community & crystalized the direction of my career. Register: https://t.co/O5ayqIzsrM https://t.co/72x3P8hQgG