• Mashup Score: 11

    Background:Beta-adrenergic antagonists or blockers (BB) are a cornerstone of cardiac therapy for multiple indications. However, BB are considered relatively contraindicated in amyloid cardiomyopathy due to poor tolerance. This intolerance is hypothesized to be due to concomitant neuropathy and significant restrictive cardiomyopathy. This study analyzes the incidence and characteristics of BB…

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    • RT @CampbellMDPhD: 🚨Beta-blocker Tolerance in Amyloid Cardiomyopathy💔 Now published @FrontCVMedicine! https://t.co/XhPd9o3NUJ Excellent wo…

    • 🚨Beta-blocker Tolerance in Amyloid Cardiomyopathy💔 Now published @FrontCVMedicine! https://t.co/XhPd9o3NUJ Excellent work from OSU Comprehensive #Amyloidosis Clinic led by @OSUWexMed med students @stuart_ramsell & Carlos Arias-Bermudez! #cardioonc #cardiotwitter #MedTwitter https://t.co/ZKMocBNVLR

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    Officially endorsed by the International Society of Cardio Oncology. Officially endorsed by the Heart Failure Society of America. The opinions presented in this educational activity do not necessarily reflect the opinions or recommendations of the HFSA.This conference will be offered as a Live Webinar only (Based on Central Standard Time Zone)   7:45am Zoom opens for…

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    • Enjoy this special issue? Join us for the @WUSTLmed 2022 #Amyloidosis LIVE CME Webinar this Saturday, March 12th! Keynotes - Dr. Wechalekar @UCL - Dr. Ahmad @NMCardioVasc Multidisciplinary care ⚕️ Session for patients/family/caregivers Register https://t.co/2DnAxklENS https://t.co/4BeUMWgkxL https://t.co/b5vYHXXW0U

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    Diagnoses of amyloidosis, particularly transthyretin amyloid cardiomyopathy (ATTR-CM), are steadily increasing throughout the world but the condition remains underdiagnosed. Patients with amyloidosis may present to a range of medical and surgical specialties, often with multi-system disease, and a high index of clinical suspicion is required for diagnosis. Bone scintigraphy and cardiovascular…

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    • To begin: "When to suspect and how to approach a diagnosis of #amyloidosis" by Drs. Steven Law & Julian Gillmore @UCL -Red Flags🚩 -Non-invasive investigation🔬 -Cardiac❤️evaluation -When to biopsy https://t.co/P4JkABjCBC 2/11 https://t.co/p8DNHg8BL0

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    Cardiac amyloidosis (CA) results in symptoms of heart failure, atrial and ventricular arrythmias, conduction disturbances, and profound autonomic dysfunction. These symptoms present unique management challenges as compared to patients without CA and can be very debilitating. Thus, management of the cardiovascular symptoms of these patients plays a central role in their care. This review presents…

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    • "Management of Cardiac ❤️ Symptoms in #Amyloidosis" by Drs. Philip King @wustlcardfellow & Andy Kates @akates1 -Heart failure💔 -Atrial Fibrillation⚡️ -Ventricular arrhythmias💞 -Pacemakers & Devices -Orthostatic Hypotension -Aortic Stenosis https://t.co/uBoX6uA4EX 3/11 https://t.co/5268y1nat1

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    Systemic amyloidosis is characterized by extracellular deposition of insoluble fibrillar proteins in multiple tissues, frequently at a distance from the site of synthesis. The two most common forms, light chain (AL) and transthyretin (ATTR) amyloidosis can cause peripheral neuropathy and, rarely, myopathy. Diagnosis can be challenging, and abundant suspicion is required to identify patients. As…

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    • "Neuromuscular 🧠🦵Complications of Systemic #Amyloidosis" by Drs. Dina Namiranian & Stefanie Geisler @WashUNeurology -Neuropathy types: autonomic, sensorimotor, others -Frequent hATTR misdiagnoses 😬 -Neuropathy diagnostics & findings 🔬 https://t.co/NnVIOmnqe4 4/11 https://t.co/mwIrzlqJ1y

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    Amyloidosis is a heterogeneous disease that can cause a wide array of non-specific symptoms when involving the gastrointestinal (GI) tract including weight loss, early satiety, change in bowel habits with diarrhea, constipation or alternating bowel pattern. Endoscopy with biopsy for Congo red staining establishes the diagnosis and fibril subtyping helps to guide targeted treatment options. Light…

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    • "Evaluation & Management Strategies for GI Involvement with #Amyloidosis" by Drs. Cassandra Fritz @cfritzMD & Elizabeth Blaney @EJBlaney @WUSTLmed -GI presentation 🤢 -Endoscopic diagnosis 🔎 -Gastroparesis, diarrhea, constipation💩 management https://t.co/HZzOMNgoTC 5/11 https://t.co/wnTEjyUdiv

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    Multiple myeloma, light-chain (AL) amyloidosis and other plasma cell dyscrasias are characterized, in part, by abnormal production of paraproteins that are often responsible for the sequelae of those diseases. These paraproteins are whole or fragmented immunoglobulins produced by clonal antibody-secreting cells (usually plasma cells but occasionally B lymphocytes). Significant heterogeneity…

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    • "What do the Elevated Protein Levels Mean in my Patient with Myeloma🦴, #Amyloidosis, & Related Disorders? by Drs. Scott Goldsmith @ScottG_MD & Keith Stockerl-Goldstein @CyclingDoctor -Protein Electrophoresis -Immunotyping -Free light chains ⛓️ https://t.co/wpLRibp0SF 6/11 https://t.co/VWvn1X7R5F

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    The management of immunoglobulin light chain (AL) amyloidosis is complex. Emerging data has shown promising results for several novel agents. We review the management of AL amyloidosis including factors that determine transplant eligibility, treatment options for transplant ineligible patients, and treatment options for relapsed/refractory AL amyloidosis. For carefully selected patients, high…

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    • "Update on Current Therapy in Conjunction with Stem Cell Transplant 🩸 for Light Chain #Amyloidosis" by Drs. Maya Abdallah @MayaAbdallah_MD & Vaishali Sanchorawala @vsanchorawala @BU_Amyloidosis -Transplant & med regimens💊 -Relapsed AL options https://t.co/C5evaFQJl5 7/11 https://t.co/tfRni84Vay