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Mashup Score: 2
Rationale: Dysanapsis refers to a mismatch between airway tree caliber and lung size arising early in life. Dysanapsis assessed by computed tomography (CT) is evident by early adulthood and associa…
Source: www.atsjournals.orgCategories: General Medicine News, PulmonologyTweet
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Mashup Score: 0
Dysanapsis, the mismatch between airway tree caliber and lung volume, is suggested by computed tomography (CT) imaging or inferred by spirometry showing a reduced ratio of FEV 1 to FVC with normal FEV 1 and increased FVC in healthy individuals. Dysanaptic growth was initially termed by Green and colleagues in 1974 to describe disproportionate growth of airway caliber and lung size leading to normal variations in maximal expiratory flows (1). As we increasingly recognize the role of early lung development
Source: www.atsjournals.orgCategories: General Medicine News, PulmonologyTweet-
Unraveling Dysanapsis: Genetic Insights into Airway Lung Mismatch and COPD @atscommunity 🔓 Open Access 🔗 https://t.co/WZzHCi3Eka
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Mashup Score: 5Increased Muc5AC and Decreased Ciliated Cells in Severe Asthma Partially Restored by Inhibition of IL-4Rα Receptor - 6 day(s) ago
Rationale: The role of IL-13 on the airway epithelium in severe asthma leading to airway remodeling remains poorly understood. Objectives: To study IL-13–induced airway remodeling on goblet cells a…
Source: www.atsjournals.orgCategories: General Medicine News, PulmonologyTweet-
The Blue Journal thanks Jonathan Boomer, MT (ASCP), PhD, for his contribution to the December 15 issue Increased Muc5AC and Decreased Ciliated Cells in Severe Asthma Partially Restored by Inhibition of IL-4Rα Receptor @MarioCas64 @KUMedCenter 🔗 https://t.co/Njf0vESHgH https://t.co/Phh9nKBUjT
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Mashup Score: 8Increased Muc5AC and Decreased Ciliated Cells in Severe Asthma Partially Restored by Inhibition of IL-4Rα Receptor - 6 day(s) ago
Rationale: The role of IL-13 on the airway epithelium in severe asthma leading to airway remodeling remains poorly understood. Objectives: To study IL-13–induced airway remodeling on goblet cells a…
Source: www.atsjournals.orgCategories: General Medicine News, PulmonologyTweet-
Increased Muc5AC and Decreased Ciliated Cells in Severe Asthma Partially Restored by Inhibition of IL-4Rα Receptor IL-13 drives airway remodeling in severe asthma by increasing mucin and decreasing cilia. Dupilumab restores the cilia @MarioCas64 🔗 https://t.co/t91eu1aaFG https://t.co/wZgo77A7HO
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Mashup Score: 17Breaking up Mucus Plugs in Asthma - 6 day(s) ago
Mucus plugs lead to bad outcomes in asthma. In fatal asthma, mucus plugs occlude airways, blocking gas exchange to cause asphyxia and death (1, 2). In exacerbations, mucus plugs occlude major airways and contribute to air trapping, atelectasis, and treatment unresponsiveness (3). These severe consequences reflect the profound impact of mucus plugs in asthma and the need for treatment advances. The identification of phenotypic and endotypic characteristics of populations with asthma who are at risk for
Source: www.atsjournals.orgCategories: General Medicine News, PulmonologyTweet-
Breaking up Mucus Plugs in Asthma @atscommunity 🔓 Open Access 🔗 https://t.co/LEB4mvNDQc https://t.co/tqJtc2SsIU
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Mashup Score: 6The Road Less Traveled: Slow but Steady Progress Toward Cystic Fibrosis Gene Therapy by the UK Respiratory Gene Therapy Consortium - 6 day(s) ago
In the United States and Europe, late preclinical and clinical stages of gene therapy product development have historically depended on funding from investor-backed biopharmaceutical companies. Initial proof-of-concept studies for putative investigational new drugs are often completed in academia, but these institutions typically lack the resources that are required for the preclinical investigational new drug–enabling pharmacology-toxicology studies, current good manufacturing practice manufacturing of
Source: www.atsjournals.orgCategories: General Medicine News, PulmonologyTweet-
The Road Less Traveled: Slow but Steady Progress Toward Cystic Fibrosis Gene Therapy by the UK Respiratory Gene Therapy Consortium 🔓 Open Access 🔗 https://t.co/OKvm0fgeM9 https://t.co/PKiLpO4LLs
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Mashup Score: 1Lentiviral Gene Therapy for Cystic Fibrosis: A Promising Approach and First-in-Human Trial - 6 day(s) ago
Cystic fibrosis (CF) is a genetic disease caused by mutations in the CFTR (cystic fibrosis transmembrane conductance regulator) gene. Although CF is a multiorgan disease, the leading causes of morb…
Source: www.atsjournals.orgCategories: General Medicine News, PulmonologyTweet-
Lentiviral Gene Therapy for Cystic Fibrosis: A Promising Approach and First-in-Human Trial @atscommunity 🔓Open Access 🔗 https://t.co/xRAndYChAk https://t.co/4t8yy6FDgB
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Mashup Score: 5ATS Blue Journal (@atsblueeditor.bsky.social) - 10 day(s) ago
Posting content from the American Journal of Respiratory and Critical Care Medicine; follows do not indicate endorsement. #pulmCC #sleepmed #AJRCCM #RespEd #ATS https://www.atsjournals.org/journal/ajrccm
Source: bsky.appCategories: General Medicine News, PulmonologyTweet-
We are now on Bluesky! 🦋 https://t.co/rbapKeQLXC https://t.co/RAZEsxAkRF
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Mashup Score: 23
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Source: www.atsjournals.orgCategories: General Medicine News, PulmonologyTweet-
The latest issue of the #AJRCCM is now live! Take a look: 🔗 https://t.co/igPVBZvYtl https://t.co/utPKgVSNw2
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Mashup Score: 1
Dr. John Fleetham chats with Dr. Ludovico Messineo and Dr. Simon Joosten about their articles “Hypnotics on Obstructive Sleep Apnea Severity and Endotypes: A Systematic Review and Meta-Analysis” and “The Arousal Threshold: The ‘Weakest Link’ in OSA Pathogenesis.”
Source: share.transistor.fmCategories: General Medicine News, PulmonologyTweet-
Don't miss the latest episode of #OutoftheBlue! This week's episode: Hypnotics on Obstructive Sleep Apnea Severity and Endotypes: A Systematic Review and Meta-Analysis” and “The Arousal Threshold: The ‘Weakest Link’ in O... Listen Here 🔈 https://t.co/xpTsLX4kaF
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The Blue Journal thanks Catherine L. Debban, PhD, for her contribution to the December 15 issue Dysanapsis Genetic Risk Predicts Lung Function Across the Lifespan https://t.co/HXm3Nn12gq https://t.co/CFq7e5JNAn