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Mashup Score: 5CRISPR-Edited, Off-the-Shelf CAR T-Cell Therapy Shows Proof of Concept in Renal Cell Carcinoma - 6 day(s) ago
Evidence from a small early trial called COBALT-RCC provides proof of concept for use of an allogeneic off-the-shelf CD70-targeted CAR T-cell therapy called CTX130 in patients with advanced clear cell…
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Mashup Score: 6HPV Screening Intervals for Cervical Cancer May Be Safely Extended Beyond Current 5-Year Recommendation, Study Finds - 6 day(s) ago
A new study has found the risk of cervical precancer 8 years after a negative HPV screening result was comparable to the risk at 3 years after a negative standard cytology screening, the current bench…
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Mashup Score: 1
Treatment with metformin may be associated with a lower risk of developing myeloproliferative neoplasms over time, according to a recent study.
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Mashup Score: 7Survival Outcomes Following Adjuvant Therapy in Patients With Clinical T2N0 Rectal Adenocarcinoma - 6 day(s) ago
Adjuvant therapy may be underutilized in patients with clinical T2N0 rectal adenocarcinoma, according to new findings presented at Digestive Disease Week 2024.
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Mashup Score: 1
Gallbladder cancer rates have been stable or declining for most Americans over the past two decades, but cases have steadily risen among Black Americans, with growing numbers of cases not being diagno…
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Mashup Score: 2
On May 16, the FDA announced the final withdrawal of the approval of infigratinib (Truseltiq) for previously treated patients with unresectable, locally advanced, or metastatic cholangiocarcinoma with…
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Mashup Score: 2
A research team identified the degree to which initial FDA approvals of cancer drugs based on immature overall survival data were subsequently followed by reporting of overall survival results.
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Mashup Score: 4Advanced Gastric or Gastroesophageal Junction Cancer: Addition of Relatlimab to Immunochemotherapy - 7 day(s) ago
The phase II RELATIVITY-060 study looked at the addition of the LAG-3–blocking antibody relatlimab to first-line nivolumab plus chemotherapy in patients with locally advanced, unresectable, or metasta…
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Mashup Score: 3
The investigational bispecific antibody linvoseltamab (targeting BCMA and CD3) achieved high response rates with acceptable safety in heavily pretreated patients with relapsed or refractory multiple m…
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Mashup Score: 4Adding Perioperative Nivolumab to Neoadjuvant Chemotherapy in Resectable NSCLC: CheckMate 77T - 8 day(s) ago
Interim analysis in the phase III CheckMate 77T trial has shown that the addition of perioperative nivolumab to neoadjuvant chemotherapy improved event-free survival in patients with resectable NSCLC.
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CRISPR-Edited, Off-the-Shelf CAR T-Cell Therapy Shows Proof of Concept in Renal Cell Carcinoma https://t.co/lZGIvzd1IK #kcsm #kidneycancer #RCC #oncology #immunotherapy #genetics