To Close or not to Close PFOs in Cryptogenic Stroke, an Evolving Question
A matter of intense debate in the last decades, the ideal strategy for secondary prevention in patients with cryptogenic stroke and patent foramen ovale (PFO) is not yet clearly defined. PFOs are prevalent in the general population and can be found in up to 40% of patients with cryptogenic stroke. 1 1. Lechat P, Mas JL, Lascault G, Loron PH, Theard M, Klimczac M, et al. Prevalence of patent foramen ovale in patients with stroke. N Engl J Med. 1988;318(18):1148-52. Although in some cases of cryptogenic