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Mashup Score: 5Prolonged lenalidomide maintenance therapy improves the depth of response in multiple myeloma - 2 year(s) ago
Key Points. Lenalidomide maintenance increases the depth of response in myeloma, promoting the achievement of MRD negativity with a survival benefit.The monitor
Source: American Society of HematologyCategories: Hem/Oncs, Latest HeadlinesTweet
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Mashup Score: 137'We are ready to go': FDA OKs J&J and Legend's BCMA CAR-T, setting stage for showdown with Bristol Myers - 2 year(s) ago
Move over, Bristol Myers Squibb. After delaying their decision by three months to review new information, the FDA has cleared Johnson & Johnson and Legend’s BCMA CAR-T rival cilta-cel, setting the stage for a showdown in multiple myeloma. Cilta-cel — which will be sold as Carvykti — marks the industry’s
Source: Endpoints NewsCategories: Hem/Oncs, Latest HeadlinesTweet-
Cilta-cel gets the regulatory approval, great news for #mmsm patients! @JanssenUS @sloan_kettering @IMFmyeloma @theMMRF @ASH_hematology @ASCO https://t.co/FEqXEpkDpz
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Cilta-cel FDA approved for multiple myeloma! CARVYKTI, priced at $465,000, which is higher than ABECMA Exciting news for the myeloma community #mmsm #cartsm https://t.co/gaMxdsAjVT
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'We are ready to go': FDA OKs J&J and Legend's BCMA CAR-T, setting stage for showdown with Bristol Myers - https://t.co/IeSEt52YpH #mmsm #myeloma #USMRC @kczmj @leshune @NausheenAhmedMD @aksinghmd @Haytham_Samy @KUcancercenter #MedTwitter
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Awaiting more details on the label. But the first report I can find on the approval is here @Nicole_DeFeudis @endpts https://t.co/X8d4ErJOs6
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Cilta-Cel approved for myeloma! #mmsm #bmtsm #celltherapy #cart @ManniMD1 @EagleMyeloma "FDA OKs J&J and Legend's BCMA CAR-T, setting stage for showdown with Bristol Myers" https://t.co/NWowlN348g
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Breaking: FDA approves cilta cel for relapsed refractory myeloma. This is great news for myeloma patients. https://t.co/X8d4ErJOs6
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Mashup Score: 2Assessment of Molecular Residual Disease Using Circulating Tumor DNA to Identify Multiple Myeloma Patients at High Risk of Relapse - 2 year(s) ago
BackgroundDespite treatment with high-dose chemotherapy followed by autologous stem cell transplantation (AHCT), patients with multiple myeloma (MM) invariably relapse. Molecular residual disease (MRD)-negativity post-AHCT has emerged as an important prognostic marker predicting the duration of remission. Current techniques for MRD assessment involve bone marrow (BM) aspirate sampling, which is…
Source: FrontiersCategories: Hem/Oncs, Latest HeadlinesTweet
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Mashup Score: 2Pretreatment serum level of interleukin-6 predicts carfilzomib-induced hypertension in relapsed/refractory multiple myeloma - 2 year(s) ago
(2022). Pretreatment serum level of interleukin-6 predicts carfilzomib-induced hypertension in relapsed/refractory multiple myeloma. Leukemia & Lymphoma. Ahead of Print.
Source: Taylor & FrancisCategories: Hem/Oncs, Latest HeadlinesTweet
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Mashup Score: 15Identification of patients at high risk of secondary extramedullary multiple myeloma development - 2 year(s) ago
The British Journal of Haematology publishes original research papers in clinical, laboratory and experimental haematology. The Journal also features annotations, reviews, short reports, images in haematology and Letters to the Editor.
Source: Wiley Online LibraryCategories: Hem/Oncs, Latest HeadlinesTweet
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Mashup Score: 1CAR-T efficacy: is conditioning the key? - 2 year(s) ago
In this issue of Blood, Hirayama and colleagues report that a favorable cytokine profile induced by lymphodepletion is associated with durable remissions in pat
Source: American Society of HematologyCategories: Hem/Oncs, Latest HeadlinesTweet
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Mashup Score: 0Microlyse: a thrombolytic agent that targets VWF for clearance of microvascular thrombosis - 2 year(s) ago
von Willebrand factor (VWF) platelet-binding activity is proteolytically regulated by ADAMTS13, with congenital or acquired deficiency in ADAMTS13 causing throm
Source: American Society of HematologyCategories: Hem/Oncs, Latest HeadlinesTweet
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Mashup Score: 12Outcomes of VDPACE with an immunomodulatory agent as a salvage therapy in relapsed/refractory multiple myeloma with extramedullary disease - 2 year(s) ago
Extramedullary disease (EMD) is an aggressive form of multiple myeloma (MM). Confirming the presence of plasma cells outside the bone marrow makes the diagnosis of EMD. There is no clear consensus on…
Source: Wiley Online LibraryCategories: Hem/Oncs, Latest HeadlinesTweet
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Mashup Score: 2Genomic analysis of high-risk smoldering multiple myeloma - 2 year(s) ago
Smoldering myeloma is an asymptomatic plasma cell dyscrasia with a heterogeneous propensity to progress to active myeloma. In order to investigate the biology of smoldering myeloma patients with high risk of progression, we analyzed the genomic characteristics …
Source: PubMed Central (PMC)Categories: Hem/Oncs, Latest HeadlinesTweet
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Mashup Score: 0
Melflufen plus dexamethasone showed superior progression-free survival than pomalidomide plus dexamethasone in patients with relapsed or refractory multiple myeloma.
Source: The Lancet HaematologyCategories: Hem/Oncs, Latest HeadlinesTweet
Prolonged lenalidomide maintenance therapy improves the depth of response in multiple myeloma https://t.co/Ea6vwbR0Rg #mmsm #myeloma #MedEd #MedTwitter #USMRC https://t.co/w6GHpR4D33