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Mashup Score: 2
Highlights • Human cardiac slices cultured with SB216763 showed reduced conduction velocity and decreased excitability, as measured by dVm/dtmax, at 3 and 24 hours compared to slices cultured in co…
Categories: Cardiac Surgery, Latest HeadlinesTweet
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Mashup Score: 0LncRNA-ZFAS1 Promotes Myocardial Ischemia-Reperfusion Injury Through DNA Methylation-Mediated Notch1 Down-Regulation in Mice: - 2 year(s) ago
Highlights • The increase of ZFAS1 expression in MIRI is an important cause of cardiomyocyte apoptosis and ROS production. • ZFAS1 can directly interact with the promoter region of Notch1, recruit …
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How does LncRNA-ZFAS1 promote myocardial ischemia reperfusion injury? Find out in #JACCBTS: https://t.co/L39qVInTo8 #IHD #openaccess #BasicResearch #TranslationalScience #CardioTwitter https://t.co/y465VGOhtI
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Mashup Score: 4Plasminogen Activator Inhibitor-1–Positive Platelet-Derived Extracellular Vesicles Predicts MACE and the Proinflammatory SMC Phenotype: - 2 year(s) ago
Highlights • This study shows the existence of PAI-1+ PEVs. Approximately 20% of plasma PAI-1 is composed of PAI-1+ PEVs. • Elevated PAI-1+ PEV levels were predictive of 1-year major adverse cardia…
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Can PAI-1+ PEV levels predict adverse cardiac events? Find out in #JACCBTS: https://t.co/GR5apM6y8l #cvCAD #openaccess #BasicResearch #TranslationalScience #CardioTwitter https://t.co/oyifzVX7kH
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Mashup Score: 5Interstitial Collagen Loss, Myocardial Remodeling, and Function in Primary Mitral Regurgitation: - 2 year(s) ago
Highlights • The stretch of volume overload in PMR initiates interstitial collagen loss and decrease in LV sphericity index. • LV chamber diastolic function is normal whereas LA function, LV twist/…
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Changes in structural architecture of the heart in chronic primary mitral regurgitation. https://t.co/7D0CfMOAp3 #JACCBTS #vhdMR #cvVHD #openaccess #BasicResearch #TranslationalScience #CardioTwitter https://t.co/s5bxEU75rZ
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Mashup Score: 3Micro RNA-411 Expression Improves Cardiac Phenotype Following Myocardial Infarction in Mice: - 2 year(s) ago
Highlights • miR-411 overexpression increases cardiomyocyte proliferation and survival. • Direct myocardial injection of miR-411 improves cardiac function and remodeling following myocardial infarc…
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How does miR-411 induce cardiomyocyte proliferation? Find out in #JACCBTS: https://t.co/j835p55shN #cvMI #HeartFailure #BasicScience #TranslationalScience #openaccess #research #CardioTwitter https://t.co/txlsKDmYP5
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Mashup Score: 2Propionate Alleviates Abdominal Aortic Aneurysm by Modulating Colonic Regulatory T-Cell Expansion and Recirculation: - 2 year(s) ago
Highlights • SCFAs alleviate the progression of AAA in both Ca3(PO4)2- and elastase-induced mouse AAA models. • Propionate expands the pool of Tregs in the cLP and enhances the cell-intrinsic abili…
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Can a gut bacteria derived metabolite activate protective #Tcells in the gut that then protect against abdominal aortic aneurysm formation? Learn more in this issue of #JACCBTS: https://t.co/Mb1UdUgWLH #CardioImmunology #BasicScience #TranslationalScience #MedTwitter https://t.co/7A9heaosJq
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Mashup Score: 0Therapeutics That Promote Sympathetic Reinnervation Modulate the Inflammatory Response After Myocardial Infarction: - 2 year(s) ago
Highlights • Quantitative multiplex immunohistochemistry employing 23 antibodies was used to identify the immune cells present in the left ventricle 2 weeks after ischemia-reperfusion. • Two therap…
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Can restoring sympathetic innervation & modulating cardiac immune phenotype reduce infarct size in a mouse model of myocardial infarction? Learn more in this issue of #JACCBTS: https://t.co/EIUChBOTig #CardioImmunology #BasicScience #TranslationalScience #CardioTwitter #cvMI https://t.co/au41eHk4cS
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Mashup Score: 4JACC: Basic to Translational Science: Vol 7, No 9 - 2 year(s) ago
ORIGINAL RESEARCH – PRECLINICAL Micro RNA-411 Expression Improves Cardiac Phenotype Following Myocardial Infarction in Mice Original Research – Preclinical …
Source: www.jacc.orgCategories: Expert Picks, Latest HeadlinesTweet-
ICYMI: Browse #JACCBTS' new special issue that highlights therapies that harness DNA and RNA therapeutics to target cardiovascular disease. https://t.co/xrM8VzxNat #BasicScience #TranslationalScience #CVD #CardioTwitter #GeneTherapy #GeneEditing https://t.co/e1JOslCcXf
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Mashup Score: 6Circulating Hepatocyte Growth Factor Reflects Activation of Vascular Repair in Response to Stress: - 2 year(s) ago
Highlights • HGF is released by stressed human vascular cells and promotes vascular cell repair responses in autocrine and/or paracrine ways. • Subjects with a low capacity to express HGF in respon…
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ICYMI: What is the role of hepatic growth factor in vascular repair? Find out in the latest issue of #JACCBTS: https://t.co/fLTH2cwBFr #openaccess #BasicScience #TranslationalScience #cvMI #atherosclerosis #CardioTwitter https://t.co/bRmtO1s10A
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Mashup Score: 9Iron Overload via Heme Degradation in the Endoplasmic Reticulum Triggers Ferroptosis in Myocardial Ischemia-Reperfusion Injury: - 2 year(s) ago
Highlights • It remains unknown how ferroptosis, triggered by excessive lipid peroxides via iron overload, is induced in I/R injury. • GPx4, an endogenous suppressor of ferroptosis, is reduced in t…
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Hypoxia and H/R result in GPx4 down-regulation and HO-1 up-regulation, both of which work cooperatively to trigger ferroptosis in I/R injury through iron overload in the ER. https://t.co/ED8V0jVNBN #JACCBTS #cvAMI #STEMI #CardioTwitter #BasicScience #TranslationalScience https://t.co/Nzvrhv6CUk
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How does GSK-3 regulation affect human cardiac #electrophysiology? Find out in #JACCBTS: https://t.co/5r5YrE131Y #cvEP #EPeeps #openaccess #BasicResearch #TranslationalScience #CardioTwitter https://t.co/fbCFUMTpYd