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    The oral, small-molecule Wee1 kinase inhibitor adavosertib was clinically active but not well tolerated by more than half the patients with recurrent or persistent uterine serous carcinoma in the phase IIb ADAGIO trial. The findings were reported at the Society of Gynecologic Oncology (SGO) 2023 Annual Meeting on Women’s Cancer by Joyce F. Liu, MD, MPH, Associate Chief and Director of Clinical…

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    • Poor Tolerability Appears to Hinder Benefit of Adavosertib in Uterine Serous Carcinoma https://t.co/TqWnbldci1 #gyncsm #uterinecancer #oncology #SGO23 #SGOmtg @SGO_org

  • Mashup Score: 5

    In patients with recurrent low-grade serous ovarian cancer, treatment with ribociclib plus letrozole was not only active, but led to outcomes that are comparable to those achieved with current agents—with a particularly striking 19-month duration of response—according to Brian M. Slomovitz, MD, Professor of Obstetrics and Gynecology at Florida International University and Director of Gynecologic…

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    • RT @ASCOPost: GOG 3026: Durable Responses With Ribociclib Plus Letrozole in Low-Grade Serous Ovarian Cancer https://t.co/YTLwAiiWer #gyncsm…

    • GOG 3026: Durable Responses With Ribociclib Plus Letrozole in Low-Grade Serous Ovarian Cancer https://t.co/YTLwAiiWer #gyncsm #ovariancancer #oncology #SGO23 #SGOmtg @SGO_org