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Mashup Score: 26Phylodynamics for cell biologists - 3 year(s) ago
Advances in experimental approaches for single-cell analysis allow in situ sequencing, genomic barcoding, and mapping of cell lineages within tissues and organisms. Large amounts of data have thus accumulated and present an analytical challenge. Stadler et al. recognized the need for conceptual and computational approaches to fully exploit these technological advances for the understanding of…
Source: ScienceCategories: Future of Medicine, Latest HeadlinesTweet
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Mashup Score: 8Making sense of neural development by comparing wiring strategies for seeing and hearing - 3 year(s) ago
Neural development builds diverse circuits out of a common toolkit, with shared mechanisms, transcription factors, and cellular signaling systems. Sitko and Goodrich compare and contrast the development of visual and olfactory systems to parse the similarities in logic and the differences in sensory information processing. Science , this issue p. [eaaz6317][1] ### BACKGROUND Since its infancy…
Source: ScienceCategories: Future of Medicine, Latest HeadlinesTweet-
The ability to perceive & interact with the world depends on an array of neural circuits. How do they acquire their characteristic properties? A new #SciMagReview explores this question by comparing development of the circuitry for seeing & hearing. ($) https://t.co/eeHuMiJ3P6 https://t.co/euUtHTuH0p
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Mashup Score: 39Making sense of neural development by comparing wiring strategies for seeing and hearing - 3 year(s) ago
Neural development builds diverse circuits out of a common toolkit, with shared mechanisms, transcription factors, and cellular signaling systems. Sitko and Goodrich compare and contrast the development of visual and olfactory systems to parse the similarities in logic and the differences in sensory information processing. Science , this issue p. [eaaz6317][1] ### BACKGROUND Since its infancy…
Source: ScienceCategories: Future of Medicine, Latest HeadlinesTweet-
The ability to perceive & interact with the world depends on an array of neural circuits. How do they acquire their characteristic properties? A new #SciMagReview explores this question by comparing development of the circuitry for seeing & hearing. ($) https://t.co/eeHuMiJ3P6 https://t.co/9ZLrnnQisC
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Mashup Score: 9Clocks, cancer, and chronochemotherapy - 3 year(s) ago
Circadian clocks help to coordinate physiological processes with the daily cycles of light and dark and periods of feeding, activity, and rest. Being out of sync with such 24-hour cycles can have unhealthy effects. Sancar and Van Gelder review the available evidence regarding circadian disruption and predisposition to cancer and circadian variations in response to cancer chemotherapy. The…
Source: ScienceCategories: Future of Medicine, Latest HeadlinesTweet
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Mashup Score: 0Clocks, cancer, and chronochemotherapy - 3 year(s) ago
Circadian clocks help to coordinate physiological processes with the daily cycles of light and dark and periods of feeding, activity, and rest. Being out of sync with such 24-hour cycles can have unhealthy effects. Sancar and Van Gelder review the available evidence regarding circadian disruption and predisposition to cancer and circadian variations in response to cancer chemotherapy. The…
Source: ScienceCategories: Future of Medicine, Latest HeadlinesTweet
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Mashup Score: 26Protein storytelling through physics - 3 year(s) ago
Computational molecular physics (CMP) aims to leverage the laws of physics to understand not just static structures but also the motions and actions of biomolecules. Applying CMP to proteins has required either simplifying the physical models or running simulations that are shorter than the time scale of the biological activity. Brini et al. reviewed advances that are moving CMP to time scales…
Source: ScienceCategories: Future of Medicine, Latest HeadlinesTweet
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Mashup Score: 26
Conversion of light energy into chemical energy ultimately drives most biochemistry on earth. Photosynthetic organisms use diverse chemical and biological structures to harvest light in different environmental contexts. Croce and van Amerongen synthesized recent structural and spectroscopic work on photosystem complexes from oxygenic photosynthetic organisms. To best capture light, photosystems…
Source: ScienceCategories: Future of Medicine, Latest HeadlinesTweet
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Mashup Score: 7Poverty, depression, and anxiety: Causal evidence and mechanisms - 3 year(s) ago
Mental equilibrium is essential for an economically productive life in both industrialized and developing countries. Accumulating evidence shows that mental ill-health and poverty tend to be traveling partners, but which is the cause? Ridley et al. reviewed the literature on natural and controlled economic experiments involving individuals living in poverty. The authors sought to resolve the…
Source: ScienceCategories: Future of Medicine, Latest HeadlinesTweet
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Mashup Score: 4Poverty, depression, and anxiety: Causal evidence and mechanisms - 4 year(s) ago
Mental equilibrium is essential for an economically productive life in both industrialized and developing countries. Accumulating evidence shows that mental ill-health and poverty tend to be traveling partners, but which is the cause? Ridley et al. reviewed the literature on natural and controlled economic experiments involving individuals living in poverty. The authors sought to resolve the…
Source: ScienceCategories: Future of Medicine, Latest HeadlinesTweet
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Mashup Score: 20The role of the microbiota in human genetic adaptation - 4 year(s) ago
The microbiota of mammals is a product of coevolution. However, humans exhibit a range of adaptive peculiarities that can be quite geographically specific. The human microbiota also displays a variety of community compositions and a range of overlapping and redundant metabolic characteristics that can alter host physiology. For example, lactase persistence is a genetic characteristic of European…
Source: ScienceCategories: Future of Medicine, Latest HeadlinesTweet
"Tree thinking" meets #CellBiology: In a new #SciMagReview, researchers evaluate ideas taken from phylodynamics of infectious disease & show how similar tree-building techniques can be applied to monitoring changes in somatic cell lineages. Learn more: ($) https://t.co/kyhteW3PU8 https://t.co/IIEYnEeHeX