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Mashup Score: 1For better drugs, diversify clinical trials - 3 year(s) ago
COVID-19 has highlighted the devastating disparities that exist for Black, Latinx, and Indigenous people in health care and medicine in the United States and other parts of the world. As a result, the importance of ethnic diversity in clinical trials has entered public discourse. This moral issue is enough to warrant elevation. But there are also scientific considerations because a lack of…
Source: ScienceCategories: Future of Medicine, Latest HeadlinesTweet
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Mashup Score: 31Designing the right protection - 3 year(s) ago
Olefins are used to manufacture our everyday essentials, including plastics, detergents, and hand sanitizers. Olefins are conventionally produced from crude oil cracking, but environmental concerns drive the urgent search for alternative, more sustainable carbon feedstocks. Carbon-containing waste streams ranging from biomass to industrial carbon dioxide (CO2) to municipal waste are increasingly…
Source: ScienceCategories: Future of Medicine, Latest HeadlinesTweet
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Mashup Score: 63Superspreading genomes - 3 year(s) ago
Individual contributions to epidemic spread vary. Although some infections may not cause any secondary cases, others are associated with so-called “superspreading” events in which numerous infections result from the same case. These events can shape the course of an epidemic, but their detection remains challenging. On page 588 of this issue, Lemieux et al. ([ 1 ][1]) show that phylogenetic…
Source: ScienceCategories: Future of Medicine, Latest HeadlinesTweet-
Using a rich sequence dataset from the early stages of the Boston #COVID19 outbreak, a new Science study identified superspreading events in specific settings and analyzed them phylogenetically. This #SciMagPerspective takes a closer look at the research: https://t.co/gCZxLYViYL https://t.co/oX7XdXtGOc
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Mashup Score: 1For better drugs, diversify clinical trials - 3 year(s) ago
COVID-19 has highlighted the devastating disparities that exist for Black, Latinx, and Indigenous people in health care and medicine in the United States and other parts of the world. As a result, the importance of ethnic diversity in clinical trials has entered public discourse. This moral issue is enough to warrant elevation. But there are also scientific considerations because a lack of…
Source: ScienceCategories: Future of Medicine, Latest HeadlinesTweet
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Mashup Score: 10Sex differences in immune responses - 3 year(s) ago
Evidence increasingly indicates that male sex is a risk factor for more severe disease and death from COVID-19. Male bias in COVID-19 mortality is observed in nearly all countries with available sex-disaggregated data, and the risk of death in males is ∼1.7 times higher than in females ([ 1 ][1]). Aging is strongly associated with higher risk of death in both sexes, but at all ages above 30…
Source: ScienceCategories: Future of Medicine, Latest HeadlinesTweet
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Mashup Score: 2Lessons in antiviral immunity - 3 year(s) ago
The adaptive branch of the immune system can kill virally infected cells and generate protective immune memory, which is the basis of vaccination strategies. Both T cell and B cell responses are important in controlling viruses and the development of immunity. However, the COVID-19 pandemic is revealing widely varying immune responses and diverse clinical outcomes with severe acute respiratory…
Source: ScienceCategories: Future of Medicine, Latest HeadlinesTweet
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Mashup Score: 4Increased tropical cyclone risk to coasts - 3 year(s) ago
The record-breaking 2020 North Atlantic hurricane season has brought new attention to tropical cyclone (TC) risk. Although the astounding total of 30 named storms is not necessarily a signature of climate change, anthropogenic climate change is increasing the threat posed by TCs in other ways. The most confidently predictable changes in TC activity with warming are an increase in the occurrence…
Source: ScienceCategories: Future of Medicine, Latest HeadlinesTweet-
Tropical cyclones are devastating & costly natural disasters, w/nearly a third of the world’s population currently living within their reach. And the risk is rising, as storms are tracking closer to land globally, a new study finds. ($) https://t.co/MEmfWh1x1q #SciMagPerspective https://t.co/ybLZ49uKdH
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Mashup Score: 28Insights from SARS-CoV-2 sequences - 3 year(s) ago
As severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread across the globe, so have efforts to sequence its RNA genome. More than 260,000 sequences are now available in public databases, about a year after the viral genome was first sequenced ([ 1 ][1]). These sequences and their associated metadata have allowed researchers to estimate the timing of SARS-CoV-2 spillover into…
Source: ScienceCategories: Future of Medicine, Latest HeadlinesTweet
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Mashup Score: 99Lessons in antiviral immunity - 3 year(s) ago
The adaptive branch of the immune system can kill virally infected cells and generate protective immune memory, which is the basis of vaccination strategies. Both T cell and B cell responses are important in controlling viruses and the development of immunity. However, the COVID-19 pandemic is revealing widely varying immune responses and diverse clinical outcomes with severe acute respiratory…
Source: ScienceCategories: Future of Medicine, Latest HeadlinesTweet
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Mashup Score: 5Increased tropical cyclone risk to coasts - 3 year(s) ago
The record-breaking 2020 North Atlantic hurricane season has brought new attention to tropical cyclone (TC) risk. Although the astounding total of 30 named storms is not necessarily a signature of climate change, anthropogenic climate change is increasing the threat posed by TCs in other ways. The most confidently predictable changes in TC activity with warming are an increase in the occurrence…
Source: ScienceCategories: Future of Medicine, Latest HeadlinesTweet-
Tropical cyclones are devastating & costly natural disasters, w/nearly a third of the world’s population currently living within their reach. And the risk is rising, as storms are tracking closer to land globally, a new study finds. ($) https://t.co/MEmfWh1x1q #SciMagPerspective https://t.co/wxKfxh8UvN
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The lack of diversity in clinical trials hinders the ability to fully understand variation and predict drug outcomes across populations, including those at most risk for a disease, a new #SciMagPerspective argues. Read more: https://t.co/LsV6thmdoL https://t.co/VmFRlsgpo2