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Mashup Score: 100Plant pangenomes for crop improvement, biodiversity and evolution - Nature Reviews Genetics - 2 month(s) ago
Plant pangenomes have had a transformative impact on crop enhancement, biodiversity conservation and evolutionary research. This Review delves into the application of plantĀ pangenomes for understanding trait diversity, aiding breeding, biodiversity classification and monitoring, and illuminating evolutionary innovations.
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Mashup Score: 181The origin and evolution of Wnt signalling - Nature Reviews Genetics - 2 month(s) ago
This Review discusses the evolutionary origin of Wnt signalling, its ancestral function and the characteristics of the primal Wnt ligand. It emphasizes the importance of genomic studies in pre-metazoan and basal metazoan species to understanding the evolutionary origin of signalling pathways.
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Mashup Score: 12Genomics for monitoring and understanding species responses to global climate change - Nature Reviews Genetics - 2 month(s) ago
Species and communities can respond to global climate change by genetically adapting to new environmental conditions, by shifting their range or through phenotypic plasticity. This Review summarizes approaches that apply and integrate omics tools to experimentally investigate, monitor and predict these species responses.
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Mashup Score: 44Methods and applications for single-cell and spatial multi-omics - Nature Reviews Genetics - 2 month(s) ago
In this Review, the authors discuss the latest advances in profiling multiple molecular modalities from single cells, including genomic, transcriptomic, epigenomic and proteomic information. They describe the diverse strategies for separately analysing different modalities, how the data can be computationally integrated, and approaches for obtaining spatially resolved data.
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Mashup Score: 139Sequencing and characterizing short tandem repeats in the human genome - Nature Reviews Genetics - 3 month(s) ago
This Review describes tools and approaches for characterizing short tandem repeats in the human genome from whole-genome sequencing data. Furthermore, the authors discuss how these recent developments have helped to better understand the effect of short tandem repeats on human health and disease.
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Mashup Score: 13Genomics for monitoring and understanding species responses to global climate change - Nature Reviews Genetics - 3 month(s) ago
Species and communities can respond to global climate change by genetically adapting to new environmental conditions, by shifting their range or through phenotypic plasticity. This Review summarizes approaches that apply and integrate omics tools to experimentally investigate, monitor and predict these species responses.
Source: www.nature.comCategories: General Medicine News, Future of MedicineTweet-
Genomics for monitoring and understanding species responses to global climate change https://t.co/hIQMrjYZbT #Review by @LouBernatchez, @AL_Ferchaud, @Chloe_Berger05, @ClareVenney & @AmandaXuereb23 Free to read here: https://t.co/FlOTqTyfox (+ a sneak peek at our March coveršļø) https://t.co/na3vY3tve0
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Mashup Score: 25Shaping faces: genetic and epigenetic control of craniofacial morphogenesis - Nature Reviews Genetics - 3 month(s) ago
Differences in facial morphology distinguish vertebrates. Here, Selleri and Rijli discuss advances in multi-omics and single-cell technologies linking genes, transcriptional networks and epigenetic landscapes to the establishment of facial patterning and its variation, with an emphasis on normal and abnormal craniofacial morphogenesis.
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Mashup Score: 152The diversification of methods for studying cellācell interactions and communication - Nature Reviews Genetics - 3 month(s) ago
In this Review, the authors summarize recent progress in cellācell interaction (CCI) research. They describe theĀ recent evolution in computational tools that underpin CCI studies, discuss improvements in experimental methods enabling more high-throughput analyses ofĀ CCIs, and highlight future directions for the field.
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Mashup Score: 25More than a decade of genetic research on the Denisovans - 3 month(s) ago
Nature Reviews Genetics – Ancient DNA studies over the past decade have yielded a plethora of insights into the Denisovan archaic hominin group. The authors review our understanding of Denisovan…
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Mashup Score: 78The expanding diagnostic toolbox for rare genetic diseases - Nature Reviews Genetics - 3 month(s) ago
Genomic technologies have greatly improved the diagnosis of rare genetic diseases. Here, the authors review emerging approaches for the identification of disease-causal genetic variants as well as omic technologies that show great potential for variant interpretation.
Source: www.nature.comCategories: General Medicine News, Future of MedicineTweet
Plant pangenomes for crop improvement, biodiversity and evolution https://t.co/DEINnE2IpI #Review by @SchreiberMona, @murukarthickj, @Nils__Stein & Martin Mascher @Uni_MR @LeibnizIPK @UniHalle @idiv