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Mashup Score: 8
Massimo (Max) Loda discusses his team’s research on the role of the microenvironment in prostate cancer progression, published in Nature Communications. The study focuses on the stroma’s significance in prostate carcinogenesis. Utilizing mouse models and human tumors, they performed single-cell RNA sequencing to analyze stromal cells in different stages of prostate cancer. The research revealed…
Source: www.urotoday.comCategories: General Medicine News, UrologyTweet
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Mashup Score: 6Novel 18-Gene Urine Test Improves Detection of Clinically Significant Prostate Cancer - Jeffrey Tosoian - 15 day(s) ago
Jeffrey Tosoian presents a new tool in prostate cancer diagnosis with the development and validation of an 18-gene urine test designed to identify clinically significant prostate cancer published in JAMA Oncology. This research, supported by the Prostate Cancer Foundation (PCF) and the NCI Early Detection Research Network, introduces a novel approach to enhancing the accuracy of prostate cancer…
Source: www.urotoday.comCategories: General Medicine News, General NewsTweet
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Mashup Score: 9The Efficacy and Resistance-Breaking Potential of EPI-7386 Masofaniten in Castration-Resistant Prostate Cancer - Andrew Laccetti - 23 day(s) ago
Zach Klaassen engages Andrew Laccetti in a discussion about Masofaniten (EPI-7386), a pioneering anti-androgen therapy targeting the N-terminal domain of the androgen receptor, aimed at overcoming resistance mechanisms observed with current prostate cancer treatments. Detailing the progression from preclinical data to clinical trials, Dr. Laccetti highlights Masofaniten’s potential synergy with…
Source: www.urotoday.comCategories: General Medicine News, General NewsTweet-
The efficacy and resistance-breaking potential of EPI-7386 masofaniten in castration-resistant #ProstateCancer. @alaccetti @MSKCancerCenter joins @zklaassen_md @GACancerCenter discussing the continuous effort to refine hormonal therapy in #PCa management > https://t.co/2XdNrgusyy https://t.co/JiN4btrbRi
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Mashup Score: 6Advancing Prostate Cancer Surgery with PSMA Imaging and Fluorescent Guidance "Presentation" - Peter Carroll - 29 day(s) ago
At the 2024 UCSF-UCLA PSMA Conference, Peter Carroll highlights the shift in prostate cancer treatment from surgery for low-risk patients to active surveillance and targeted treatment for higher-risk groups, emphasizing the importance of novel imaging like PSMA PET in improving outcomes. He advocates for personalized treatment strategies based on detailed risk assessments and the potential…
Source: www.urotoday.comCategories: General Medicine News, General NewsTweet
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Mashup Score: 4AI-Based PTEN Loss Assessment: A Multicenter Retrospective Study on Prostate Cancer Metastasis - Tamara Jamaspishvili - 1 month(s) ago
Tamara Jamaspishvili delves into her group’s study on PTEN loss as an early predictor of prostate cancer metastasis post-surgery. The study employs artificial intelligence to enhance the accuracy of PTEN loss assessment, traditionally done manually by pathologists. Dr. Jamaspishvili explains that PTEN, a tumor suppressor gene, is a critical biomarker for aggressive prostate cancer. Her team’s…
Source: www.urotoday.comCategories: General Medicine News, General NewsTweet-
AI-based PTEN loss assessment: a multicenter retrospective study on #ProstateCancer metastasis. Tamara Jamaspishvili @UpstateNews and @AndreaMiyahira @PCFnews discuss her group's study on PTEN loss as an early predictor of #PCa metastasis post-surgery > https://t.co/NgxrZYOfUz https://t.co/Oyde6THUpC
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Mashup Score: 3The Hidden Mechanisms Behind Rapid Tumor Evolution: AR Amplification on Extrachromosomal DNA I Prostate Cancer - Scott Dehm - 1 month(s) ago
Andrea Miyahira engages with Scott Dehm to discuss his research on AR gene alterations in endocrine therapy-resistant prostate cancer. In collaboration with teams from multiple universities, including Princeton and UCSF, Dr. Dehm examines the frequent AR gene alterations in castration-resistant prostate cancers. Utilizing linked-read DNA sequencing, the study confirms that a subset of these…
Source: www.urotoday.comCategories: General Medicine News, General NewsTweet
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Mashup Score: 7Distinct Mesenchymal Cell States Mediate Prostate Cancer Progression - Massimo Loda - 1 month(s) ago
Massimo (Max) Loda discusses his team’s research on the role of the microenvironment in prostate cancer progression, published in Nature Communications. The study focuses on the stroma’s significance in prostate carcinogenesis. Utilizing mouse models and human tumors, they performed single-cell RNA sequencing to analyze stromal cells in different stages of prostate cancer. The research revealed…
Source: www.urotoday.comCategories: General Medicine News, UrologyTweet-
Distinct mesenchymal cell states mediate #ProstateCancer progression. @MassimoLodaMD @WCMCPathology and @AndreaMiyahira @PCFnews discuss his team’s research on the role of the microenvironment in #PCa progression, published in @NatureComms > https://t.co/xlVJqm99c9 @nyphospital https://t.co/H8lSb8Qzuy
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Mashup Score: 9The Efficacy and Resistance-Breaking Potential of EPI-7386 Masofaniten in Castration-Resistant Prostate Cancer - Andrew Laccetti - 2 month(s) ago
Zach Klaassen engages Andrew Laccetti in a discussion about Masofaniten (EPI-7386), a pioneering anti-androgen therapy targeting the N-terminal domain of the androgen receptor, aimed at overcoming resistance mechanisms observed with current prostate cancer treatments. Detailing the progression from preclinical data to clinical trials, Dr. Laccetti highlights Masofaniten’s potential synergy with…
Source: www.urotoday.comCategories: General Medicine News, General NewsTweet-
The efficacy and resistance-breaking potential of EPI-7386 masofaniten in castration-resistant #ProstateCancer. @alaccetti @MSKCancerCenter joins @zklaassen_md @GACancerCenter discussing the continuous effort to refine hormonal therapy in #PCa management > https://t.co/2XdNrgusyy https://t.co/JiN4btrbRi
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Mashup Score: 6Advancing Prostate Cancer Surgery with PSMA Imaging and Fluorescent Guidance "Presentation" - Peter Carroll - 2 month(s) ago
At the 2024 UCSF-UCLA PSMA Conference, Peter Carroll highlights the shift in prostate cancer treatment from surgery for low-risk patients to active surveillance and targeted treatment for higher-risk groups, emphasizing the importance of novel imaging like PSMA PET in improving outcomes. He advocates for personalized treatment strategies based on detailed risk assessments and the potential…
Source: www.urotoday.comCategories: General Medicine News, General NewsTweet
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Mashup Score: 6AI-Based PTEN Loss Assessment: A Multicenter Retrospective Study on Prostate Cancer Metastasis - Tamara Jamaspishvili - 2 month(s) ago
Tamara Jamaspishvili delves into her group’s study on PTEN loss as an early predictor of prostate cancer metastasis post-surgery. The study employs artificial intelligence to enhance the accuracy of PTEN loss assessment, traditionally done manually by pathologists. Dr. Jamaspishvili explains that PTEN, a tumor suppressor gene, is a critical biomarker for aggressive prostate cancer. Her team’s…
Source: www.urotoday.comCategories: General Medicine News, General NewsTweet-
AI-based PTEN loss assessment: a multicenter retrospective study on #ProstateCancer metastasis. Tamara Jamaspishvili @UpstateNews and @AndreaMiyahira @PCFnews discuss her group's study on PTEN loss as an early predictor of #PCa metastasis post-surgery > https://t.co/NgxrZYOfUz https://t.co/Oyde6THUpC
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Distinct mesenchymal cell states mediate #ProstateCancer progression. @MassimoLodaMD @WCMCPathology and @AndreaMiyahira @PCFnews discuss his team’s research on the role of the microenvironment in #PCa progression, published in @NatureComms > https://t.co/xlVJqm99c9 @nyphospital https://t.co/H8lSb8Qzuy