Antimicrobial resistance (AMR) is one of the top 10 global public health threats facing humanity. AMR threatens the effective prevention and treatment of an ever-increasing range of infections caused by bacteria, parasites, viruses and fungi. It occurs when microorganisms develop resistance to medicines that are relied upon for treatment, making some conditions difficult or impossible to cure. As a result, infections persist in the body, increasing the risk of disease spread, severe illness and death. The Antimicrobial Resistance channel offers learning resources to support implementation of the *Global Action Plan on AMR* (2015), by building health care worker competencies to help combat AMR in their daily clinical practice.