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    The combination of carfilzomib, lenalidomide, and dexamethasone (KRd) did not improve progression-free survival in patients with newly diagnosed myeloma absent a high-risk disease prognosis, compared with the standard of care–bortezomib, lenalidomide, and dexamethasone (VRd). The data from a planned interim analysis for the ENDURANCE (E1A11) randomized phase three trial will be presented at the…

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    • Carfilzomib does not improve outcomes in newly diagnosed myeloma compared to bortezomib. Planned interim analysis of efficacy & toxicity in @eaonc E1A11 Ph3 RCT VRd vs KRd https://t.co/vXf1LHQtDB #mmsm #NCT01863550 #ASCO20 Abstract LBA3 https://t.co/kvpeSXWJf7 n=1087 @myelomaMD