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Mashup Score: 9Circulating tumor DNA and plasma microsatellite instability during PD-1 blockade - Kasi - Journal of Gastrointestinal Oncology - 4 year(s) ago
Circulating tumor DNA and plasma microsatellite instability during PD-1 blockade
Source: jgo.amegroups.comCategories: Hem/Oncs, Latest HeadlinesTweet
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Mashup Score: 0The Cancer Plus Daily - 4 year(s) ago
A selection of articles, blog posts, videos and photos recommended by Wafik El-Deiry MDPhD
Source: paper.liCategories: Hem/Oncs, Latest HeadlinesTweet
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Mashup Score: 0How I treat MSI cancers with advanced disease - 4 year(s) ago
Mismatch repair deficiency (dMMR) results in microsatellite instability (MSI) and is strongly associated with responsiveness to programmed death-1 receptor (PD-1)-blocking antibodies. Probably the main driver for the observed high efficacy of immune checkpoint inhibitors in dMMR tumours is the remarkably high tumour mutational burden. MSI can be detected using immunohistochemistry and/or PCR. In…
Source: Esmo OpenCategories: Hem/Onc News and JournalsTweet
🆕 Paper published today! 💡Can we use #liquidbiopsies to assess #immunotherapy response early❓ Not☝🏽but 2 ways: 1️⃣ #ctDNA kinetics VAF% 📈progression 🆚 response📉2-3 weeks into treatment! 2️⃣Plasma-#MSI; not tissue but🩸 MSI✔️➡️✖️💭 @OncoAlert @ASCO https://t.co/bBG8Ipz0PW https://t.co/qUuF9FUC3R