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    The Cancer Plus Daily - 4 year(s) ago

    A selection of articles, blog posts, videos and photos recommended by Wafik El-Deiry MDPhD

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    Mismatch repair deficiency (dMMR) results in microsatellite instability (MSI) and is strongly associated with responsiveness to programmed death-1 receptor (PD-1)-blocking antibodies. Probably the main driver for the observed high efficacy of immune checkpoint inhibitors in dMMR tumours is the remarkably high tumour mutational burden. MSI can be detected using immunohistochemistry and/or PCR. In…

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    • How I treat #MSI cancers with advanced disease The Daily Tweet #TDT Christoph Zielinski ESMO - European Society for Medical Oncology https://t.co/uHqB342v1T