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Mashup Score: 1
PURPOSE The aim of the current study was to assess the economic impact of using next-generation sequencing (NGS) versus single-gene testing strategies among patients with metastatic non–small-cell lung cancer (mNSCLC) from the perspective of the Centers for Medicare & Medicaid Services (CMS) and US commercial payers. METHODS A decision analytic model considered patients who were newly diagnosed…
Source: JCO Precision OncologyCategories: Hem/Oncs, Latest HeadlinesTweet
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Mashup Score: 1Podcasts - 2 year(s) ago
ASCO Podcasts deliver timely information to keep you up to date on the latest changes, challenges, and advances in oncology. Listen on the go to interviews and insights from thought leaders, innovators, and experts in oncology.
Source: ASCOCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
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Mashup Score: 1Targeting Anaplastic Lymphoma Kinase in GI Primary Malignancies - 2 year(s) ago
In the era of precision oncology, tumors are increasingly profiled and treated on the basis of their molecular signatures as opposed to the primary site of origin. The anaplastic lymphoma kinase (ALK) signaling pathway, initially discovered in anaplastic large cell lymphoma, has been the poster child for targeted therapy development. The ALK receptor tyrosine kinase is associated with downstream…
Source: JCO Precision OncologyCategories: Hem/Oncs, Latest HeadlinesTweet
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Mashup Score: 2
PURPOSE The aim of the current study was to assess the economic impact of using next-generation sequencing (NGS) versus single-gene testing strategies among patients with metastatic non–small-cell lung cancer (mNSCLC) from the perspective of the Centers for Medicare & Medicaid Services (CMS) and US commercial payers. METHODS A decision analytic model considered patients who were newly diagnosed…
Source: JCO Precision OncologyCategories: Hem/Oncs, Latest HeadlinesTweet
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Mashup Score: 1JCO Precision Oncology Celebrates 5 Years Capturing the Emergence of Personalized Cancer Care - 2 year(s) ago
“In our first 5 years, we’ve impacted both the study and the practice of precision oncology and been able to highlight both successes and remaining challenges in the field, helping us to focus on areas for future study,” said founding editor-in-chief Dr. James M. Ford.
Source: ASCO ConnectionCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
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Mashup Score: 0Real-World Performance of a Comprehensive Genomic Profiling Test Optimized for Small Tumor Samples - 2 year(s) ago
PURPOSE Tissue-based comprehensive genomic profiling (CGP) is increasingly used for treatment selection in patients with advanced cancer; however, tissue availability may limit widespread implementation. Here, we established real-world CGP tissue availability and assessed CGP performance on consecutively received samples. MATERIALS AND METHODS We conducted a post hoc, nonprespecified analysis of…
Source: JCO Precision OncologyCategories: Hem/Oncs, Latest HeadlinesTweet
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Mashup Score: 0Landscape and Clonal Dominance of Co-occurring Genomic Alterations in Non–Small-Cell Lung Cancer Harboring MET Exon 14 Skipping - 2 year(s) ago
PURPOSE MET exon 14 skipping alterations (METex14) comprise a diverse set of actionable oncogene drivers in non–small-cell lung cancer (NSCLC). Recent studies have established the efficacy of tyrosine kinase inhibitors for this patient population. The landscape of co-occurring genetic alterations in METex14 NSCLC and their potential impact to therapeutic sensitivities has not yet been fully…
Source: JCO Precision OncologyCategories: Hem/Oncs, Latest HeadlinesTweet
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Mashup Score: 0Coronavirus (COVID-19) | ASCO Publications - 3 year(s) ago
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Source: ascopubs.orgCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
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Mashup Score: 0Implementation and Clinical Utility of an Integrated Academic-Community Regional Molecular Tumor Board - 3 year(s) ago
Purpose Precision oncology develops and implements evidence-based personalized therapies that are based on specific genetic targets within each tumor. However, a major challenge that remains is the provision of a standardized, up-to-date, and evidenced-based precision medicine initiative across a geographic region. Materials and Methods We developed a statewide molecular tumor board that…
Source: JCO Precision OncologyCategories: Hem/Oncs, Latest HeadlinesTweet
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Mashup Score: 0Role of Community-Based Genomics Programs - 3 year(s) ago
Article Tools EDITORIALS …
Source: JCO Precision OncologyCategories: Hem/Oncs, Latest HeadlinesTweet
Economic Impact of Next-Generation Sequencing [NGS] vs Single-Gene Testing to Detect Genomic Alterations in Metastatic NSCLC Using a Decision Analytic Model [May 16, 2019] @n8pennell et al. #JCOPO @ASCO_pubs https://t.co/SSoA9FuLg1 #hpeonc #lcsm #PrecisionMedicine https://t.co/gleSTJAOg3