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Mashup Score: 0A transcriptome‐wide association study identifies novel candidate susceptibility genes for prostate cancer risk - 3 year(s) ago
Although an estimated 58 percent of prostate cancers are linked to familial factors, most heritable risk variants for prostate cancer remain unidentified. In this transcriptome-wide association study…
Source: Wiley Online LibraryCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
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Mashup Score: 0
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Source: Wiley Online LibraryCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
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Mashup Score: 24The custom transcriptome - 4 year(s) ago
The panorama of human phenotypes arises from a mix of common and rare genetic variants, some of which affect how genes are expressed and spliced throughout the body. More than a decade ago, scientists aiming to better understand the effects of genetic diversity in healthy individuals launched the Genotype-Tissue Expression (GTEx) Consortium. Here, Science unveils the third and final phase of the…
Source: ScienceCategories: Future of Medicine, Latest HeadlinesTweet
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Mashup Score: 0
Some human genetic variants affect the amount of RNA produced and the splicing of gene transcripts, crucial steps in development and maintaining a healthy individual. However, some of these changes only occur in a small number of tissues within the body. The Genotype-Tissue Expression (GTEx) project has been expanded over time, and, looking at the final data in version 8, Aguet et al. present a…
Source: ScienceCategories: Healthcare Professionals, Latest HeadlinesTweet
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Mashup Score: 6The Genotype-Tissue Expression Project - 4 year(s) ago
The panorama of human phenotypes arises from a mix of common and rare genetic variants, some of which affect how genes are expressed and spliced throughout the body. More than a decade ago, scientists aiming to better understand the effects of genetic diversity in healthy individuals launched the…
Source: Science | AAASCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
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Mashup Score: 0The custom transcriptome - 4 year(s) ago
The panorama of human phenotypes arises from a mix of common and rare genetic variants, some of which affect how genes are expressed and spliced throughout the body. More than a decade ago, scientists aiming to better understand the effects of genetic diversity in healthy individuals launched the Genotype-Tissue Expression (GTEx) Consortium. Here, Science unveils the third and final phase of the…
Source: ScienceCategories: Future of Medicine, Latest HeadlinesTweet
NOW ONLINE | Duo Liu et al In this #TWAS, data from the #GTEx Project was used to construct models for investigating associations between genetically determined #GeneExpression & #prostatecancer risk ➡️https://t.co/SweXSDo2pf @UHCancerCenter @VUMC_Medicine @KeckMedUSC @UMNews https://t.co/86hcNYra1P