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Mashup Score: 1JNCCN - 7 month(s) ago
JNCCN
Source: jnccn.orgCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
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Mashup Score: 0Reply to S. Sorscher - 10 month(s) ago
AUTHORS’ DISCLOSURES OF POTENTIAL CONFLICTS OF INTEREST The following represents disclosure information provided by authors of this manuscript. All relationships are considered compensated unless otherwise noted. Relationships are self-held unless noted. I = Immediate Family Member, Inst = My Institution. Relationships may not relate to the subject matter of this manuscript. For more information about ASCO’s conflict of interest policy, please refer to www.asco.org/rwc or ascopubs.org/jco/authors/author-ce
Source: ascopubs.orgCategories: Hem/Onc News and Journals, Latest HeadlinesTweet-
💭 #JCO #CorrespondenceReplies: Reply to S Sorsche ➡️ https://t.co/lycVnfS0Fe #gencsm @VivekSubbiah
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Mashup Score: 4Journal of Clinical Oncology (JCO) Podcast - 10 month(s) ago
The Journal of Clinical Oncology features discussions of new and noteworthy results published in ASCO’s Journal of Clinical Oncology and how they impact clinical practice and research, hosted by Dr. Shannon Westin.
Source: jcopodcast.libsyn.comCategories: Hem/Onc News and Journals, Latest HeadlinesTweet-
✅ out JCO After Hours Podcast🎙️ w/ @ShannonWestin. We discuss racial & ethnic differences in clinical multigene #GermlineTesting in pts w/ Early-Onset #ColorectalCancer w/ @drholowatyj @VUMC_Cancer 👉 https://t.co/4duiHBSrXK #CRCSM #gencsm #EAOCRC #HereditaryGICancer #GeneChat
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Mashup Score: 3Rare Germline ATM Variants Influence the Development of Chronic Lymphocytic Leukemia - 2 year(s) ago
PURPOSE Germline missense variants of unknown significance in cancer-related genes are increasingly being identified with the expanding use of next-generation sequencing. The ataxia telangiectasia–mutated (ATM) gene on chromosome 11 has more than 1,000 germline missense variants of unknown significance and is a tumor suppressor. We aimed to determine if rare germline ATM variants are more…
Source: Journal of Clinical OncologyCategories: Hem/Onc News and Journals, Latest HeadlinesTweet-
🧐 #JCO #BiologyOfNeoplasia: Germline ATM variants are uniquely abundant in 24% of #ChronicLymphcyticLeukemia patients and impact the CLL phenotype 👉 https://t.co/lycIOFaXiz #leusm #GenCSM @DanaFarber https://t.co/rnsXbGF5vQ
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Mashup Score: 2Nonsurgical Options for Risk Reduction of Contralateral Breast Cancer in BRCA Mutation Carriers With Early-Stage Breast Cancer - 2 year(s) ago
Early data suggest that prophylactic breast RT reduces contralateral cancers in BRCA mutation carriers
Source: Journal of Clinical OncologyCategories: Hem/Onc News and Journals, Latest HeadlinesTweet-
🤔 #JCO #CommentsAndControversies: Early data suggest prophylactic breast #RadiationTherapy reduces contralateral #BreastCancer in #BRCA mutation carriers ➡️ https://t.co/CCDfSnZzDc #BCSM #gencsm #radonc #prevention https://t.co/91w7UvVD98
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Mashup Score: 2Genomic Microsatellite Signatures Identify Germline Mismatch Repair Deficiency and Risk of Cancer Onset - 2 year(s) ago
PURPOSE Diagnosis of Mismatch Repair Deficiency (MMRD) is crucial for tumor management and early detection in patients with the cancer predisposition syndrome constitutional mismatch repair deficiency (CMMRD). Current diagnostic tools are cumbersome and inconsistent both in childhood cancers and in determining germline MMRD. PATIENTS AND METHODS We developed and analyzed a functional Low-pass…
Source: Journal of Clinical OncologyCategories: Hem/Onc News and Journals, Latest HeadlinesTweet-
🆕 Genomic microsatellite signatures identify germline mismatch repair deficiency and risk of cancer onset 👉 https://t.co/PwSFh0wGNy #JCO #gencsm #pedcsm #ChildhoodCancer @Uri_Tabori https://t.co/9GmeHeYu58
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Mashup Score: 0
Section:It is now easier and less expensive than ever for clinicians to just order gene panel testing for anyone with suspected inherited disease, including cancer.1,2 Cancer multigene panel tests (MGPTs) range in size from just a few genes to several dozen or more. However, just because a test can be ordered, does not mean it should be. Ordering a germline genetic test is not the same as other…
Source: Journal of Clinical OncologyCategories: Hem/Onc News and Journals, Latest HeadlinesTweet-
📣 #JCO #Editorial: Who should have multigene germline testing for hereditary cancer? 👉 https://t.co/xcI29JNAAg #gencsm #BCSM #gyncsm @SharonSavageMD https://t.co/qAYGg3Xthc
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Mashup Score: 1Point/Counterpoint: Is It Time for Universal Germline Genetic Testing for All GI Cancers? - 2 year(s) ago
Use of germline genetic testing among patients with cancer is increasing because of (1) the availability of multigene panel tests that include multiple cancer susceptibility genes in a single test, (2) decreased costs of these tests and improvements in insurance coverage, and (3) US Food and Drug Administration–approval of genotype-directed therapies such as poly(ADP-ribose) polymerase inhibitors…
Source: Journal of Clinical OncologyCategories: Hem/Onc News and Journals, Latest HeadlinesTweet-
Check out what’s hot this week in #JCO: 🎤 Point/Counterpoint: Is It Time for Universal Germline #GeneticTesting for All GI Cancers? ➡️ https://t.co/1HzD1aQP74 #gencsm #CRCSM #stcsm https://t.co/GMdmlDnQSc
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Mashup Score: 4Cascade Testing for Hereditary Cancer Syndromes: Should We Move Toward Direct Relative Contact? A Systematic Review and Meta-Analysis - 2 year(s) ago
PURPOSE Evidence-based guidelines recommend cascade genetic counseling and testing for hereditary cancer syndromes, providing relatives the opportunity for early detection and prevention of cancer. The current standard is for patients to contact and encourage relatives (patient-mediated contact) to undergo counseling and testing. Direct relative contact by the medical team or testing laboratory…
Source: Journal of Clinical OncologyCategories: Hem/Onc News and Journals, Latest HeadlinesTweet-
🧐 Cascade testing for #HereditaryCancer syndromes: Should we move towards direct relative contact? A #JCO systematic review and meta-analysis 👉 https://t.co/ozkhJJCBwy #gencsm #BCSM #gyncsm https://t.co/bCuZsHRJHh
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Mashup Score: 0Good Genes - 2 year(s) ago
What if good news after genetic testing fails to provide you the answers you were searching for?
Source: Journal of Clinical OncologyCategories: Hem/Onc News and Journals, Latest HeadlinesTweet-
💙 #JCO #ArtOfOncology: What if good news after #GeneticTesting fails to provide you the answers you were searching for? https://t.co/oG1CoEp2kA #gencsm #BCSM #gyncsm @KDemarest05
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The October issue of @JNCCN is now available online! Featured: @NCCN Guidelines on #ProstateCancer, insights into recent updates to #NCCNGuidelines for Genetic/Familial High-Risk Assessment: Breast, Ovarian, and Pancreatic, and more! https://t.co/8t8aPaRYGu #PCSM #GenCSM https://t.co/A6vAcdNI4X