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Mashup Score: 2Immunotherapy Improves PFS, OS in Endometrial Cancer - 2 month(s) ago
Results of a meta-analysis support the use of immunotherapy in combination with chemotherapy as initial treatment for advanced endometrial cancer, according to researchers.
Source: www.cancertherapyadvisor.comCategories: General Medicine News, Onc News and JournalsTweet
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Mashup Score: 2Immunotherapy Improves PFS, OS in Endometrial Cancer - 2 month(s) ago
Results of a meta-analysis support the use of immunotherapy in combination with chemotherapy as initial treatment for advanced endometrial cancer, according to researchers.
Source: www.cancertherapyadvisor.comCategories: General Medicine News, Onc News and JournalsTweet
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Mashup Score: 0Metformin Use Linked to Endometrial Cancer Incidence, Outcomes - Oncology Nurse Advisor - 3 month(s) ago
A meta-analysis revealed associations between metformin use and endometrial cancer in patients with type 2 diabetes.
Source: www.oncologynurseadvisor.comCategories: General Medicine News, Onc News and JournalsTweet
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Mashup Score: 30Pathogenic germline variants in patients with endometrial cancer of diverse ancestry - 5 month(s) ago
Among 1625 patients with endometrial cancer, 216 (13%) had germline pathogenic variants, and rates of germline pathogenic variants and subsequent genetic counseling varied by both self-reported and i…
Categories: General Medicine News, Onc News and JournalsTweet
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Mashup Score: 30Pathogenic germline variants in patients with endometrial cancer of diverse ancestry - 6 month(s) ago
Among 1625 patients with endometrial cancer, 216 (13%) had germline pathogenic variants, and rates of germline pathogenic variants and subsequent genetic counseling varied by both self-reported and i…
Categories: General Medicine News, Onc News and JournalsTweet
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Mashup Score: 30Pathogenic germline variants in patients with endometrial cancer of diverse ancestry - 7 month(s) ago
Among 1625 patients with endometrial cancer, 216 (13%) had germline pathogenic variants, and rates of germline pathogenic variants and subsequent genetic counseling varied by both self-reported and i…
Categories: General Medicine News, Onc News and JournalsTweet
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Mashup Score: 27Pathogenic germline variants in patients with endometrial cancer of diverse ancestry - 7 month(s) ago
Among 1625 patients with endometrial cancer, 216 (13%) had germline pathogenic variants, and rates of germline pathogenic variants and subsequent genetic counseling varied by both self-reported and i…
Categories: General Medicine News, Onc News and JournalsTweet
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Mashup Score: 1Oral Selinexor as Maintenance Therapy After First-Line Chemotherapy for Advanced or Recurrent Endometrial Cancer - 7 month(s) ago
PURPOSE Selinexor inhibits exportin-1 (XPO1) resulting in nuclear accumulation of tumor suppressor proteins including p53 and has clinical activity in endometrial cancer (EC). The primary end point was to assess progression-free survival (PFS) with once-weekly oral selinexor in patients with advanced or recurrent EC. PATIENTS AND METHODS ENGOT-EN5/GOG-3055/SIENDO was a randomized, prospective, multicenter, double-blind, placebo-controlled, phase III study at 107 sites in 10 countries. Patients 18 years or older with histologically confirmed EC were enrolled. All had completed a single line of at least 12 weeks of taxane-platinum combination chemotherapy and achieved partial or complete response. Patients were assigned to receive 80 mg oral selinexor once weekly or placebo with 2:1 random assignment (ClinicalTrials.gov identifier: NCT03555422). RESULTS Between January 2018 and December 2021, 263 patients were randomly assigned, with 174 allocated to selinexor and 89 to placebo. The medi
Source: ascopubs.orgCategories: General Medicine News, Onc News and JournalsTweet
Results of a meta-analysis support the use of immunotherapy in combination with chemotherapy as initial treatment for advanced #endometrialCancer. Reported in @Annals_Oncology. https://t.co/fUOhL56Rcs #gyncsm