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Mashup Score: 0
In this well-characterized cohort of current and former smokers with and without COPD, we identified risk factors for suicide/overdose that emphasize the subjective experience of illness over objective assessments of lung function.
Source: PubMedCategories: Latest Headlines, PulmonologyTweet
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Mashup Score: 0Quantitative Interstitial Abnormality Progression and Outcomes in the COPDGene and PLuSS Cohorts - PubMed - 2 year(s) ago
Age at enrollment, female gender, current smoking status, and the MUC5B minor allele were associated with quantitative interstitial abnormality progression. Each percent annual increase in quantitative interstitial abnormalities was associated with annual declines in FVC (COPDGene: 8.5 mL/year, 95% …
Source: PubMedCategories: Latest Headlines, PulmonologyTweet
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Mashup Score: 410 Year Follow-up of Lung Function, Respiratory Symptoms, and Functional Capacity in the COPDGene Study - PubMed - 3 year(s) ago
Progression in FEV1, SGRQ, and 6MWD overall appears to be slow, and the change over time in groups traditionally characterized as not having disease closely mirrors that of the groups with COPD at all GOLD stages. Current cigarette smokers had greater loss of FEV1 than former smokers, while SGRQ and …
Source: PubMedCategories: Latest Headlines, PulmonologyTweet
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Mashup Score: 0
Clinically Significant and Comorbid Anxiety and Depressive Symptoms Predict Severe Respiratory Exacerbations in Smokers: A Post-Hoc Analysis of the COPDGene and SPIROMICS Cohorts
Source: PubMedCategories: Latest Headlines, PulmonologyTweet
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Mashup Score: 0
Background Chronic obstructive pulmonary disease (COPD) and bronchiectasis can overlap and share pathologic features, such as small airway disease (SAD). Whether the presence of SAD and emphysema in smokers with CT-derived bronchiectasis is associated with exacerbations is unknown. Purpose To assess …
Source: PubMedCategories: Latest Headlines, PulmonologyTweet
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Mashup Score: 0
Among participants with spirometry confirmed COPD or baseline emphysema, ACEi/ARB use was associated with slower progression of emphysema and lung function decline.
Source: PubMedCategories: Latest Headlines, PulmonologyTweet
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Mashup Score: 1
Continuous evaluation of participants in the COPDGene study will provide useful insights that will enable better identification of disease subtypes. %
Source: Pulmonology AdvisorCategories: Latest Headlines, PulmonologyTweet
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Mashup Score: 5Machine Learning Characterization of COPD Subtypes - 4 year(s) ago
COPD is a heterogeneous syndrome. Many COPD subtypes have been proposed, but there is not yet consensus on how many COPD subtypes there are and how they should be defined. The COPD Genetic Epidemiology Study (COPDGene), which has generated 10-year longitudinal chest imaging, spirometry, and molecular data, is a rich resource for relating COPD phenotypes to underlying genetic and molecular…
Source: CHESTCategories: Latest Headlines, PulmonologyTweet
#Clinical #Markers Associated with Risk of #Suicide or #Drug #Overdose Among #Heavy #Smokers - A Longitudinal Follow-Up Study of the #COPDGene #Cohort https://t.co/4HZIqunITX https://t.co/nl422XmsXl