• Mashup Score: 38

    Pernio or chilblains is characterized by erythema and swelling at acral sites (eg, toes and fingers), typically triggered by cold exposure. Clinical and histopathologic features of pernio are well described, but the pathogenesis is not entirely understood; vasospasm and a type I interferon (IFN-I) immune response are likely involved. During the coronavirus disease 2019 (COVID-19) pandemic,…

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    • #Chilblains #pernio in #covid19 ➡️#SARSCoV2 infection via cellular receptor ACE2 ➡️Affecting renin-angiotensin-aldosterone system ➡️Increase vasoconstricting, pro-inflammatory & prothrombotic angiotensin II pathway 👉🏽https://t.co/SmAPFUlp7L via @MayoProceedings #covidtoes https://t.co/QB8nptUoY0

  • Mashup Score: 0
    SRUK - 3 year(s) ago

    A chilblain is a condition which results from defective blood circulation on exposure to cold. The skin may first become itchy, then red and swollen with a burning sensation and very tender to touch. An infection may occur should the skin break down. Chilblains usually appear on the extremities fingers, toes and ears. Dampness and cold…

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    • #Chilblains ➡️Poor #circulation when exposed to #cold ➡️Usually affects #fingers, #toes, ears ➡️#Skin becomes itchy, red & swollen with burning sensation & tender ➡️Many with #Raynauds also has chilblains ✅Avoid extremes of temperature 👉🏽https://t.co/YhCwyOZcWn via @WeAreSRUK https://t.co/qRpk2Wf0eF