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Mashup Score: 9NHS to offer blood group genotype test for transfusion patients - 3 month(s) ago
People in England with sickle cell disorder and thalassaemia will have NHS access to the world’s first blood group genotyping test, it has been announced. NHS England said the testing will transform care for patients living with sickle cell disorder and thalassaemia and enable accurate matching for people who need transfusions. As part of the new system, people with sickle cell, thalassaemia and…
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Mashup Score: 5Hepatitis may trigger a treatable myeloma, researchers report - 3 month(s) ago
New treatment possibilities have emerged, inspired by a patient with multiple myeloma who appeared to be cured after treatment for hepatitis. Hepatitis C and B infection should be considered as a potential cause of this type of cancer, according to a new study. Early identification of an infection with these viruses can help doctors to prescribe appropriate treatment before it leads to malignant…
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Mashup Score: 5Obesity linked to blood cancer precursor MGUS - 3 month(s) ago
Obesity is linked to an increased risk of developing monoclonal gammopathy of undetermined significance (MGUS), according to a new analysis. Research, published in Blood Advances, found being obese was associated with 73% increased odds of having MGUS, compared with individuals within normal weight ranges. Researcher Dr David Lee, of Massachusetts General Hospital, said: “While significant…
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Mashup Score: 5Individual risk prediction model for multiple myeloma unveiled - 3 month(s) ago
A computational model for newly-diagnosed multiple myeloma predicts an individual’s prognosis based on tumour genomics and treatments, researchers have reported. Led by researchers at Sylvester Comprehensive Cancer Center, at the University of Miami Miller School of Medicine, the model, called IRMMa, improves on previous prognostic tools because it takes into account the biology of patients’…
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Mashup Score: 1Young sickle cell patients less likely to have COVID-19 vaccines - 3 month(s) ago
People with sickle cell disease have lower rates of vaccination against COVID-19 – despite the fact they have an increased risk of serious illness or death if they develop the disease, according to a new study. Analysis by Michigan Medicine, the University of Michigan’s academic medical centre, USA, found teens and children over five with sickle cell disease were far less likely than other young…
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Mashup Score: 6Key regulator of blood stem cell fate identified - 4 month(s) ago
A key regulator of haematopoietic stem cells has been identified, showing a new way in which stem cells control inflammation, researchers have reported. The study led by US researchers at Memorial Sloan Kettering Cancer Center, New York, NY, and the New York Genome Center found that a gene called SON is a key controller of blood stem cell fate. The team was led by co-first authors Dr Hanzhi Luo,…
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Mashup Score: 15Age affects diagnosis of von Willebrand disease - 4 month(s) ago
The age at which someone is tested for von Willebrand disease (VWD) significantly affects their diagnosis, according to new analysis led by Irish researchers. The findings could be important in addressing the challenges in the misdiagnosis and treatment of patients, and could help to reduce the risk of bleeding complications during surgery and childbirth, researchers say. The study, led by Dr…
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Mashup Score: 5
Faecal microbiota transplants could help to prevent graft versus host disease (GvHD) after stem cell transplantations, according to a new German study. Researchers at the Technical University of Munich and the Universitätsklinikum Regensburg (UKR) found the risk of GvHD is significantly reduced when certain microbes are present in the gut. The team was led by Dr Erik Thiele Orberg, who heads a…
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Mashup Score: 4
Offering prophylactic treatment before immunotherapy could significantly reduce the rate of cytokine release syndrome in multiple myeloma patients, a new US study has found. Treatment breakthroughs, such as the immunotherapy drug teclistamab, can lead to potentially lethal side effects, including cytokine release syndrome (CRS) and immune cell-associated neurotoxicity syndrome (ICANS). The newly…
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Mashup Score: 9Common beta blocker to be trialled for sickle cell cardiomyopathy - 4 month(s) ago
A major new study will assess if a beta blocker used to treat heart problems, haemangioma, migraines, and anxiety would benefit sickle cell disease patients, it has been announced. Researchers at Indiana University School of Medicine, USA, have been awarded a $3 million grant by the US Department of Defense to evaluate the efficacy of propranolol. Dr Ankit Desai, associate professor of medicine…
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People in England with sickle cell disorder and thalassaemia will have NHS access to the world’s first blood group genotyping test, it has been announced. Read the latest #BSHNews story here: https://t.co/EDtfH0KoLX https://t.co/0GU9AVcNgu