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Mashup Score: 3Vitamin D supplementation and major cardiovascular events: D-Health randomised controlled trial - 10 month(s) ago
Objective To investigate whether supplementing older adults with monthly doses of vitamin D alters the incidence of major cardiovascular events. Design Randomised, double blind, placebo controlled trial of monthly vitamin D (the D-Health Trial). Computer generated permuted block randomisation was used to allocate treatments. Setting Australia from 2014 to 2020. Participants 21 315 participants…
Source: The BMJCategories: General Medicine Journals and Societies, Latest HeadlinesTweet
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Mashup Score: 2
Objective To investigate the association between surgeon volume and patient outcomes after elective shoulder replacement surgery to improve patient outcomes and inform future resource planning for joint replacement surgery. Design Prospective cohort study. Setting Public and private hospitals in the United Kingdom, 2012-20. Participants Adults aged 18 years or older who had shoulder…
Source: The BMJCategories: General Medicine Journals and Societies, Latest HeadlinesTweet-
The lowest risk of reoperation and serious adverse events, including shorter hospital stays, were observed in patients who had shoulder replacements by high volume surgeons, finds new #BMJResearch https://t.co/gTIQSLcIgY @MarkosValsamis
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Mashup Score: 2
Objective To investigate the association between surgeon volume and patient outcomes after elective shoulder replacement surgery to improve patient outcomes and inform future resource planning for joint replacement surgery. Design Prospective cohort study. Setting Public and private hospitals in the United Kingdom, 2012-20. Participants Adults aged 18 years or older who had shoulder…
Source: The BMJCategories: General Medicine Journals and Societies, Latest HeadlinesTweet-
Patients treated by surgeons who averaged more than 10.4 shoulder replacements yearly had lower rates of revision surgery and reoperation, lower risk of serious adverse events, and shorter hospital stays, finds new #BMJResearch https://t.co/gTIQSLcIgY @MarkosValsamis
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Mashup Score: 6
Objective To emulate a randomized target trial to estimate the association between the antiviral drug molnupiravir and hospital admission or death in adults with SARS-CoV-2 infection in the community during the omicron predominant era who were at high risk of progression to severe covid-19. Design Emulation of a randomized target trial using electronic health records. Setting US Department of…
Source: The BMJCategories: General Medicine Journals and Societies, Latest HeadlinesTweet-
Did molnupiravir offer any benefit over no treatment in reducing hospital admission or death at 30 days in adults with SARS-CoV-2 infection who have at least one risk factor during the omicron predominant era? New #BMJResearch investigates https://t.co/KpLsEyD3zS @zalaly
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Mashup Score: 1
Objectives To address whether sparing the medial retropharyngeal lymph node (MRLN) region from elective irradiation volume provides non-inferior local relapse-free survival versus standard radiotherapy in patients with nasopharyngeal carcinoma. Design Open-label, non-inferiority, multicentre, randomised, phase 3 trial. Setting Three Chinese hospitals between 20 November 2017 and 3 December…
Source: The BMJCategories: General Medicine Journals and Societies, Latest HeadlinesTweet-
Does sparing the medial retropharyngeal lymph node region from elective irradiation volume provide better outcomes compared with standard radiotherapy in patients with nasopharyngeal carcinoma? New #BMJResearch investigates https://t.co/iEF0isfjXp
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Mashup Score: 1
Objective To evaluate the benefit of combining polygenic risk scores with the QCancer-10 (colorectal cancer) prediction model for non-genetic risk to identify people at highest risk of colorectal cancer. Design Population based cohort study. Setting Data from the UK Biobank study, collected between March 2006 and July 2010. Participants 434 587 individuals with complete data for genetics and…
Source: The BMJCategories: General Medicine Journals and Societies, Latest HeadlinesTweet-
New #BMJResearch evaluates the benefit of combining polygenic risk scores with the QCancer-10 (colorectal cancer) prediction model for non-genetic risk to identify people at highest risk of colorectal cancer https://t.co/r2Il3h88Xg
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Mashup Score: 12Post-acute sequelae of covid-19 six to 12 months after infection: population based study - 2 year(s) ago
Objectives To describe symptoms and symptom clusters of post-covid syndrome six to 12 months after acute infection, describe risk factors, and examine the association of symptom clusters with general health and working capacity. Design Population based, cross sectional study Setting Adults aged 18-65 years with confirmed SARS-CoV-2 infection between October 2020 and March 2021 notified to…
Source: The BMJCategories: General Medicine Journals and Societies, Latest HeadlinesTweet-
"As one of the largest population based studies, with a follow-up of six to 12 months after acute SARS-CoV-2 infection, we show a considerable burden of symptom clusters with sequelae also affecting younger adults . . ." New #BMJResearch @WinfriedKern https://t.co/Ac2j4x2hLq
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Mashup Score: 1
Objective To assess whether maternal ultra-processed food intake during peripregnancy and during the child rearing period is associated with offspring risk of overweight or obesity during childhood and adolescence. Design Population based prospective cohort study. Setting The Nurses’ Health Study II (NHSII) and the Growing Up Today Study (GUTS I and II) in the United States. Participants…
Source: The BMJCategories: General Medicine Journals and Societies, Latest HeadlinesTweet-
New #BMJResearch: Maternal consumption of ultra-processed food during the child rearing period is associated with an increased risk of overweight or obesity in offspring, independent of maternal and offspring lifestyle risk factors @AndyChanMD https://t.co/g0Kfjo4Ejq
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Mashup Score: 5Evaluating how clear the questions being investigated in randomised trials are: systematic review of estimands - 2 year(s) ago
Objectives To evaluate how often the precise research question being addressed about an intervention (the estimand) is stated or can be determined from reported methods, and to identify what types of questions are being investigated in phase 2-4 randomised trials. Design Systematic review of the clarity of research questions being investigated in randomised trials in 2020 in six leading general…
Source: The BMJCategories: General Medicine Journals and Societies, Latest HeadlinesTweet-
How often is the precise research question being addressed about an intervention stated in the reported methods? New #BMJResearch investigates https://t.co/q223OrMl3T
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Mashup Score: 5
Objectives To characterize individual participant level response distributions to acute monotherapy for major depressive disorder in randomized, placebo controlled trials submitted to the US Food and Drug Administration from 1979 to 2016. Design Individual participant data analysis. Population 232 randomized, double blind, placebo controlled trials of drug monotherapy for major depressive…
Source: The BMJCategories: General Medicine Journals and Societies, Latest HeadlinesTweet-
New #BMJResearch analyses individual participant level response distributions to acute monotherapy for major depressive disorder in randomised, placebo controlled trials submitted to the US FDA from 1979 to 2016 https://t.co/XalvMZxJ8F
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Vitamin D supplementation might reduce the incidence of major cardiovascular events, although the absolute risk difference was small and the confidence interval was consistent with a null finding, finds new #BMJResearch https://t.co/AwFf2ajZKY