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Mashup Score: 0A Novel LncRNA SNHG3 Promotes Osteoblast Differentiation Through BMP2 Upregulation in Aortic Valve Calcification: - 1 year(s) ago
Highlights • The long noncoding RNA SNHG3 was upregulated in the leaflets of both patients and mice with calcific aortic valve disease. • SNHG3 can associate with EZH2 in the nucleus of hVICs to ep…
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Mashup Score: 2
Highlights • Human cardiac slices cultured with SB216763 showed reduced conduction velocity and decreased excitability, as measured by dVm/dtmax, at 3 and 24 hours compared to slices cultured in co…
Categories: Cardiac Surgery, Latest HeadlinesTweet-
How does GSK-3 regulation affect human cardiac #electrophysiology? Find out in #JACCBTS: https://t.co/5r5YrE131Y #cvEP #EPeeps #openaccess #BasicResearch #TranslationalScience #CardioTwitter https://t.co/fbCFUMTpYd
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Mashup Score: 0LncRNA-ZFAS1 Promotes Myocardial Ischemia-Reperfusion Injury Through DNA Methylation-Mediated Notch1 Down-Regulation in Mice: - 2 year(s) ago
Highlights • The increase of ZFAS1 expression in MIRI is an important cause of cardiomyocyte apoptosis and ROS production. • ZFAS1 can directly interact with the promoter region of Notch1, recruit …
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How does LncRNA-ZFAS1 promote myocardial ischemia reperfusion injury? Find out in #JACCBTS: https://t.co/L39qVInTo8 #IHD #openaccess #BasicResearch #TranslationalScience #CardioTwitter https://t.co/y465VGOhtI
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Mashup Score: 4Plasminogen Activator Inhibitor-1–Positive Platelet-Derived Extracellular Vesicles Predicts MACE and the Proinflammatory SMC Phenotype: - 2 year(s) ago
Highlights • This study shows the existence of PAI-1+ PEVs. Approximately 20% of plasma PAI-1 is composed of PAI-1+ PEVs. • Elevated PAI-1+ PEV levels were predictive of 1-year major adverse cardia…
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Can PAI-1+ PEV levels predict adverse cardiac events? Find out in #JACCBTS: https://t.co/GR5apM6y8l #cvCAD #openaccess #BasicResearch #TranslationalScience #CardioTwitter https://t.co/oyifzVX7kH
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Mashup Score: 5Interstitial Collagen Loss, Myocardial Remodeling, and Function in Primary Mitral Regurgitation: - 2 year(s) ago
Highlights • The stretch of volume overload in PMR initiates interstitial collagen loss and decrease in LV sphericity index. • LV chamber diastolic function is normal whereas LA function, LV twist/…
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Changes in structural architecture of the heart in chronic primary mitral regurgitation. https://t.co/7D0CfMOAp3 #JACCBTS #vhdMR #cvVHD #openaccess #BasicResearch #TranslationalScience #CardioTwitter https://t.co/s5bxEU75rZ
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Mashup Score: 5A Phase 1 Dose-Escalation Study of the Cardiac Myosin Inhibitor Aficamten in Healthy Participants: - 2 year(s) ago
Highlights • Certain genetic hypertrophic cardiomyopathies may result from hypercontractility of cardiac muscle, caused by pathogenic variants in genes encoding proteins of the cardiac sarcomere. •…
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In this #JACCBTS clinical case, authors examine the efficacy, safety, ease of use, pharmacokinetic, and pharmacodynamic of aficamten. https://t.co/YkQ1ueQCyE #cvHCM #openaccess #BasicResearch #TranslationalResearch #CardioTwitter @MyosinMD @scottdsolomon https://t.co/cy5rYnhS1I
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Mashup Score: 9Wolters Kluwer Health - 2 year(s) ago
JavaScript Error JavaScript has been disabled on your browser. You must enable it to continue. Here’s how to enable JavaScript in the following browsers: Internet Explorer From the Tools menu, select Options Click the Content tab Select Enable JavaScript Firefox From the Tools…
Source: lww.comCategories: Latest Headlines, RheumatologyTweet-
🚨Featured Article🚨 A new #Spine #BasicResearch study found 3D-porous titanium provides a scaffold for bone formation that structurally mimics cancellous bone & improves human mesenchymal stem cell adhesion & proliferation. #OrthoTwitter #NSGY https://t.co/qNtf63p2sz
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Mashup Score: 6Outstanding Achievement Award from the ESC Council for Basic Cardiovascular Science (CBCS) - 2 year(s) ago
Honouring basic researchers in the early stage of their career
Source: www.escardio.orgCategories: Cardiology News and Journals, Latest HeadlinesTweet-
Honouring basic researchers in the early-mid stage of their career 😊 Applications for the Outstanding Achievement Awards 2022 are still open until 15 May. Make the most of this opportunity https://t.co/mste14EEXZ #ESCBasicScience #basicscience #basicresearch #ESCSoT https://t.co/61PbkrAeK3
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Mashup Score: 40The Amazing Brain: Motor Neurons of the Cervical Spine - 3 year(s) ago
Today, you may have opened a jar, done an upper body workout, played a guitar or a piano, texted a friend, or maybe even jotted down a grocery list longhand. All of these “skilled” arm, wrist, and …
Source: NIH Director's BlogCategories: Healthcare Professionals, Latest HeadlinesTweet-
To conclude my blog’s summer series, catch an unusual view of the density of certain neurons in the #cervicalspine. In the future, the #NIH BRAIN Initiative-supported #basicresearch may help people with paralysis improve arm, wrist, and hand movements. https://t.co/6b3SwCnlWP
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Mashup Score: 74Human Antibodies Target Many Parts of Coronavirus Spike Protein - 3 year(s) ago
For many people who’ve had COVID-19, the infections were thankfully mild and relatively brief. But these individuals’ immune systems still hold onto enduring clues about how best to neu…
Source: NIH Director's BlogCategories: Healthcare Professionals, Latest HeadlinesTweet-
A new study finds a successful #immune response to #COVID19 involves #antibodies that hit multiple parts of the #spike, not just the RBD. This #basicresearch could point to new ways to treat or prevent COVID19. #NIH https://t.co/Ctuc9YfHR9
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How does SNHG3 promote aortic valve calcification? Drs. Long Chen, Zhe Zheng, and colleagues work to answer this question in #JACCBTS: https://t.co/IAV9PzsVzn #openaccess #BasicResearch #TranslationalScience https://t.co/WbilFSpyVa