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Mashup Score: 0
Background: Angiotensin receptor-neprilysin inhibitor (ARNI) prescription in the United States remains suboptimal despite strong evidence for efficacy and value in heart failure with reduced ejection
Source: Circulation: Heart FailureCategories: Cardiology News and Journals, Latest HeadlinesTweet
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Mashup Score: 0Prediction of Left Ventricular Ejection Fraction Change Following Treatment With Sacubitril/Valsartan: - 1 year(s) ago
Abstract Background Sacubitril/valsartan (Sac/Val) improves left ventricular ejection fraction (LVEF) in heart failure (HF) with reduced ejection fraction regardless of previous treatments. Improve…
Source: JACC: Heart FailureCategories: Cardiologists, Latest HeadlinesTweet-
Prediction of #LVEF Change Following Treatment With Sac/Val Lower baseline LVEF, higher LVMI, longer duration of HF, and higher NTproBNP were the most significant factors that identified lack of LVEF improvement to >35% after 12 months of #ARNI use https://t.co/hYoAPELsiX https://t.co/xjxLzKOoTN
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Mashup Score: 3
Jacob B. Pierce, Zhen Li, Melissa Greiner, Steven J. Lippmann, N. Chantelle Hardy, Xian Shen, Mark Stampehl, Robert J. Mentz, Larry A. Allen, Pamela N. Peterson, Gregg C. Fonarow, Emily C. O’Brien and Stephen J. Greene Jacob B. PierceJacob B. Pierce Department of Medicine, Duke University School of Medicine, Durham, NC , Zhen LiZhen Li Department of Population Health Sciences, Duke…
Source: Circulation: Heart FailureCategories: Cardiologists, Latest HeadlinesTweet-
🚨 New #SimPub #AHA22 led by @IMResidencyDuke Jake Pierce *⃣ #ARNI use for HFmrEF/HFpEF has increased over time, but absolute use remains low *⃣ ARNI prescription concentrated at select US hospitals @AHAMeetings @AHAScience #GWTG_HF @DCRINews @CircHF https://t.co/fnkZJpPgBW https://t.co/7QAxeOe5R3
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Mashup Score: 3
Before TEER or surgery, patients with MR should be optimized on GDMT with sacubitril/valsartan for at least 6 months, say experts.
Source: TCTMD.comCategories: Cardiologists, Latest HeadlinesTweet-
#GDMT With #ARNI Lessens #MR, Perhaps Obviating Need for Interventions The use of Sac/Val in patients with #HFrEF appears to reduce the severity of #MR @TCTMD @michaelTCTMD @JJheart_doc @mirvatalasnag @JavedButler1 @GreggWStone @SJGreene_md @mmamas1973 https://t.co/Sh5Nqbw2Bz
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Mashup Score: 13Reverse Remodeling Assessed by Left Atrial and Ventricular Strain Reflects Treatment Response to Sacubitril/Valsartan: - 2 year(s) ago
Abstract Background The left ventricular global longitudinal strain (LVGLS) and left atrial reservoir strain (LARS) are considered as sensitive and reliable markers of cardiac remodeling and functi…
Source: JACC: Cardiovascular ImagingCategories: Expert Picks, Latest HeadlinesTweet-
ICYMI: In #HFrEF, #ARNI use is associated w/ complete left heart reverse remodeling (improved LA reservoir #echofirst strain & LV global longitudinal strain), which portends better prognosis. https://t.co/R5n1YqUkvS #JACCIMG #CardioTwitter #cvImaging https://t.co/pnb5cK2R1U
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Mashup Score: 3Neprilysin Inhibitors in Heart Failure: The Science, Mechanism of Action, Clinical Studies, and Unanswered Questions - 2 year(s) ago
Highlights • Neprilysin cleaves natriuretic peptides, bradykinin, adrenomedullin, substance P, angiotensin I and II, and endothelin. • In patients with very advanced HF, the downstream response to …
Categories: Cardiologists, Latest HeadlinesTweet-
This wonderful review led by Prof @BiykemB discussed about the #Neprilysin Inhibitors in #HeartFailure: The Science, Mechanism of Action, Clinical Studies, and Unanswered Questions @BiykemB @JACCJournals #JACC #ARNI #CardioTwitter @AndrewJSauer @robmentz https://t.co/GCYaFLG1W9 https://t.co/tjzFxGYF9U
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Mashup Score: 6Reverse Remodeling Assessed by Left Atrial and Ventricular Strain Reflects Treatment Response to Sacubitril/Valsartan: - 2 year(s) ago
Abstract Background The left ventricular global longitudinal strain (LVGLS) and left atrial reservoir strain (LARS) are considered as sensitive and reliable markers of cardiac remodeling and functi…
Source: JACC: Cardiovascular ImagingCategories: Expert Picks, Latest HeadlinesTweet-
In #HFrEF, #ARNI use is associated w/ complete left heart reverse remodeling (improved LA reservoir #echofirst strain & LV global longitudinal strain), which portends better prognosis. https://t.co/R5n1YqUkvS #JACCIMG #CardioTwitter #cvImaging https://t.co/JJmHhNUova
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Mashup Score: 0Medicare Coverage and Out-of-Pocket Costs of Quadruple Drug Therapy for Heart Failure: - 2 year(s) ago
Abstract Background Beta-blockers, angiotensin receptor-neprilysin inhibitor (ARNI), mineralocorticoid receptor antagonists, and sodium-glucose cotransporter-2 inhibitors (SGLT2i), known as quadrup…
Categories: Cardiologists, Latest HeadlinesTweet-
The median annual OOP cost for #HeartFailure #quadrupletherapy was $2,217. When excluding #SGLT2i or #ARNI, the median annual OOP cost dropped to $1,319 and $1,322, respectively. 1/2 https://t.co/kzlC87XS6b
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Mashup Score: 10Tolerability of Sacubitril/Valsartan in Patients With Advanced Heart Failure: Analysis of the LIFE Trial Run-In - 2 year(s) ago
Abstract Background The LIFE (LCZ696 In Hospitalized Advanced Heart FailurE) trial, which evaluated sacubitril/valsartan in patients with advanced heart failure (HF) with reduced ejection fraction …
Source: JACC: Heart FailureCategories: Cardiologists, Latest HeadlinesTweet-
Analysis of the #LIFE Trial Run-In Intolerance to low-dose Sa/Val (#ARNI) was common among subjects with advanced #HFrEF undergoing run-in for the LIFE trial, predominantly caused by #hypotension https://t.co/YD1aIjBcqP #HeartFailure #JACCHF @JACCJournals @BiykemB @JavedButler1 https://t.co/AHGp83LrCT
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Mashup Score: 22
Abstract Acute coronary syndrome (ACS) is frequently complicated by evidence of heart failure (HF). Those at highest risk for acute decompensated HF in the setting of ACS (ACS-HF) are older, female…
Source: JACC: Heart FailureCategories: Cardiologists, Latest HeadlinesTweet-
Acute Decompensated #HeartFailure in the Setting of #ACS Recent neutral findings for use of #ARNI after MI underscore the need for dedicated trials exploring the efficacy of new #GDMT in the post-MI population https://t.co/6WYmSjRBgr @JACCJournals @TexHern @DLBHATTMD #JACCHF https://t.co/I78VnOR0kB
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#GraphicalAbstract by @IkeRChinyere from the #CircHF Digital Strategies team on Clinical and Socioeconomic Determinants of #ARNI Prescription at Hospital Discharge in Patients w/ #HFrEF Full article available: https://t.co/WovNenqvyO #AHAJournals https://t.co/DZ2Bn2Eomk