In this Review, the authors introduce the application of artificial intelligence, in particular machine learning and deep learning, for improving multiple stages of MRI, including acquisition, processing and post-processing steps, for studying osteoarthritis.
Nature Reviews Rheumatology – The peptide hormone adropin, which is downregulated in dermal fibroblasts in patients with systemic sclerosis (SSc), inhibits TGFβ-mediated fibrosis in in…
Nature Reviews Rheumatology – In this Review, Knight and Erkan consider how the 2023 ACR–EULAR classification criteria for antiphospholipid syndrome (APS) can guide future research…
Nature Reviews Rheumatology – Relapsing polychondritis, a rare inflammatory disorder that affects cartilaginous structures, presents challenges in diagnosis owing to overlapping symptoms with other…
Nature Reviews Rheumatology – Granzyme serine proteases are known for their perforin-dependent cytotoxic activities, but evidence also indicates that they have a range of non-cytotoxic,…
Nature Reviews Rheumatology – Medication adherence in gout is low, and discontinuation of urate-lowering therapy puts patients at risk of flares and cardiovascular events. A…
Nature Reviews Rheumatology – Beyond the traditional classification of monogenic or complex, many genetic diseases can be considered genetically transitional disease. In this Perspective, the…
Nature Reviews Rheumatology – Rheumatoid arthritis has a substantial genetic component, some of which is associated with the presence of low-frequency or rare variants. Next-generation…
Nature Reviews Rheumatology – This Review discusses joint-specific memory (the tendency of arthritis to recur in previously inflamed joints), explores the involvement of resident memory…
Nature Reviews Rheumatology – Multidimensional and single-cell profiling of peripheral blood and inflamed tissues is a powerful and high-resolution tool for the stratification of patients…
