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Mpox has become all too familiar around the world in the past two years. But in central Africa, it’s been a recurring health threat for decades. An ongoing outbreak of mpox in the Democratic Republic of the Congo (DRC) has become larger and more widespread than any previous outbreak there, with more than 18,000 suspected and confirmed cases since January 2023. The type, or clade, of the virus behind this mpox outbreak is also more likely to cause severe illness or death than the type that caused the