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Mashup Score: 30Liquid biopsy for proliferative diabetic retinopathy: single-cell transcriptomics of human vitreous reveals inflammatory T cell signature - 22 day(s) ago
Current therapies for proliferative diabetic retinopathy (PDR) do not specifically target VEGF-independent, cell-type specific processes that lead to vision loss, such as inflammatory pathways. This study aims to identify targetable cell types, and corresponding signaling pathways, by elucidating the single cell landscape of the vitreous of patients with PDR.
Source: www.ophthalmologyscience.orgCategories: General Medicine News, OphthalmologyTweet
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Mashup Score: 32Prosthetic Visual Acuity with the PRIMA Subretinal Microchip in Patients with Atrophic Age-related Macular Degeneration at 4 years follow-up - 29 day(s) ago
To assess the efficacy and safety of the PRIMA neurostimulation system with a subretinal microchip for improving visual acuity (VA) in patients with geographic atrophy (GA) due to age-related macular degeneration (AMD) at 48-months post-implantation.
Source: www.ophthalmologyscience.orgCategories: General Medicine News, OphthalmologyTweet
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Mashup Score: 16Deep Learning-based Identification of Intraocular Pressure-Associated Genes Influencing Trabecular Meshwork Cell Morphology - 1 month(s) ago
Genome-wide association studies (GWAS) have recently uncovered many loci associated with variation in intraocular pressure (IOP). Artificial intelligence (AI) can be used to interrogate the effect of specific genetic knockouts on the morphology of trabecular meshwork cells (TMCs) and thus, IOP regulation.
Source: www.ophthalmologyscience.orgCategories: General Medicine News, OphthalmologyTweet
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Mashup Score: 182
To evaluate the safety and efficacy of CBT-001, a multi-target tyrosine kinase inhibitor (MKI) eyedrop, for pterygia.
Source: www.ophthalmologyscience.orgCategories: General Medicine News, OphthalmologyTweet
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Mashup Score: 7Ocular Signs and Testing Most Compatible with Sarcoidosis-associated Uveitis: A Latent Class Analysis - 1 month(s) ago
This study aims to explore the potential subgroups of sarcoidosis-associated uveitis (SAU) within a multicenter cohort of uveitis participants.
Source: www.ophthalmologyscience.orgCategories: General Medicine News, OphthalmologyTweet
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Mashup Score: 14An Epigenome-Wide Association Study of DNA Methylation and Proliferative Retinopathy over 28 Years in Type 1 Diabetes - 1 month(s) ago
To perform a prospective epigenome-wide association study of DNA methylation (DNAm) and 28-year proliferative diabetic retinopathy (PDR) incidence in type 1 diabetes (T1D).
Source: www.ophthalmologyscience.orgCategories: General Medicine News, OphthalmologyTweet
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Mashup Score: 54A User-Friendly Approach for the Diagnosis of Diabetic Retinopathy Using ChatGPT and Automated Machine Learning - 2 month(s) ago
To assess the capabilities of ChatGPT and Vertex AI in executing code-free preprocessing, training machine learning models, and analyzing the data.
Source: www.ophthalmologyscience.orgCategories: General Medicine News, OphthalmologyTweet
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Mashup Score: 16Role of Systemic Factors in Improving the Prognosis of Diabetic Retinal Disease and Predicting Response to Diabetic Retinopathy Treatment - 2 month(s) ago
To review clinical evidence on systemic factors that might be relevant to update diabetic retinal disease (DRD) staging systems including prediction of DRD onset, progression, and response to treatment.
Source: www.ophthalmologyscience.orgCategories: General Medicine News, OphthalmologyTweet
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Mashup Score: 13
To provide automated system for synthesizing fluorescein angiography (FA) images from color fundus (CF) photographs for averting risks associated with fluorescein dye and extend its future application to Space-associated neuro-ocular syndrome (SANS) detection in spaceflight where resources are limited.
Source: www.ophthalmologyscience.orgCategories: General Medicine News, OphthalmologyTweet-
#MachineLearning using Generative Adversarial Networks (GAN) to synthesize artificial fluorescein angiography from color fundus photos. New GAN may help on #space station to eval disc edema from Spaceflight Associated Neuro-ocular Syndrome in astronauts https://t.co/tSoHf12V6b https://t.co/y0bzZQjvSa
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Mashup Score: 17Suppression of neovascularization by topical and subconjunctival bevacizumab following high-risk corneal transplantation - 2 month(s) ago
To assess the effectiveness of topical and subconjunctival bevacizumab in suppressing vascularization in graft and host bed following high-risk corneal transplantation.
Source: www.ophthalmologyscience.orgCategories: General Medicine News, OphthalmologyTweet
Single cell analysis of human vitreous cells from vitrectomies for proliferative diabetic retinopathy revealed activated T cells make up the primary vitreous cell type with an immune cell profile distinct from peripheral blood. @RHaliyur @SurgeonRetina https://t.co/QW3qMrawqv https://t.co/T6U9uGNsFZ