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Mashup Score: 0Preparing Patients for Oral Immunotherapy (PPOINT): International Delphi consensus for procedural preparation and consent - 29 day(s) ago
Despite the promise of oral immunotherapy (OIT) to treat food allergies, this procedure is associated with potential risk. There is no current agreement about what elements should be included in the preparatory or consent process.
Source: www.jacionline.orgCategories: General Medicine News, Allergy-ImmunologyTweet
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Mashup Score: 4Immunoglobulin G4-related disease and B-cell malignancy due to an IKZF1 gain-of-function variant - 30 day(s) ago
Footnotes & These authors contributed equally to this work. Affiliations Laboratory of Immunogenetics of Human Diseases, IdiPAZ Institute for Health Research, La Paz University Hospital, Madrid, Spain Innate Immunity Group, IdiPAZ Institute for Health Research, La Paz University Hospital, Madrid, Spain Interdepartmental Group of Immunodeficiencies, Madrid, Spain Footnotes & These authors contributed equally to this work. Affiliations Department of Hematology, La Palma University Hospital, Breña Alta,
Source: www.jacionline.orgCategories: General Medicine News, General HCPsTweet
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Mashup Score: 5Preparing Patients for Oral Immunotherapy (PPOINT): International Delphi consensus for procedural preparation and consent - 30 day(s) ago
Despite the promise of oral immunotherapy (OIT) to treat food allergies, this procedure is associated with potential risk. There is no current agreement about what elements should be included in the preparatory or consent process.
Source: www.jacionline.orgCategories: General Medicine News, Allergy-ImmunologyTweet
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Mashup Score: 7Dupilumab in patients with chronic spontaneous urticaria (LIBERTY-CSU CUPID): two randomized, double-blind, placebo-controlled, phase 3 trials - 2 month(s) ago
Capsule Summary: Dupilumab significantly reduced urticaria activity in patients with CSU who were symptomatic despite H1-AH; with a trend towards improvement in patients with prior anti-IgE treatment. Safety was consistent with the known dupilumab safety profile.
Source: www.jacionline.orgCategories: General Medicine News, Allergy-ImmunologyTweet
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Mashup Score: 33Long-Term Safety of Mepolizumab in EGPA: Results From the Long-Term Access Programme - 3 month(s) ago
Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare, relapsing/remitting disease with heterogeneous manifestations. The Phase III MIRRA RCT demonstrated the safety and efficacy of anti-IL-5 therapy mepolizumab over 52 weeks, leading to approval for EGPA in adults. Data on the extended safety profile of mepolizumab in EGPA are limited. The Long-term Access Programme (LAP;MEA116841/NCT03298061) monitored the extended safety of real-word mepolizumab use in patients with EGPA.
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Mashup Score: 9
To evaluate the efficacy and safety of TLL-018, a potent and selective small molecule TYK2/JAK1 inhibitor, in chronic spontaneous urticaria (CSU) adults with inadequate response to antihistamine.
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Mashup Score: 1Posttransplantation late complications increase over time for patients with SCID: A Primary Immune Deficiency Treatment Consortium (PIDTC) landmark study - 3 month(s) ago
The Primary Immune Deficiency Treatment Consortium (PIDTC) enrolled children in the United States and Canada onto a retrospective multicenter natural history study of hematopoietic cell transplantation (HCT).
Source: www.jacionline.orgCategories: General Medicine News, Allergy-ImmunologyTweet
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Mashup Score: 0Causative mechanisms and clinical impact of immunoglobulin deficiencies in Ataxia Telangiectasia - 3 month(s) ago
Affiliations Willem-Alexander Children’s Hospital, Department of Pediatrics, Laboratory for Pediatric Immunology, Leiden University Medical Center, Leiden, the Netherlands Affiliations Willem-Alexander Children’s Hospital, Department of Pediatrics, Laboratory for Pediatric Immunology, Leiden University Medical Center, Leiden, the Netherlands Affiliations Department of Pediatric Neurology, Amalia Children’s Hospital, and Donders Institute for Brain, Cognition and Behaviour, Radboud university medical
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Mashup Score: 0Solar urticaria involves rapid mast cell STAT3 activation and neutrophil recruitment, with FcεR1 as an upstream regulator - 4 month(s) ago
Solar urticaria is a rare photodermatosis characterised by rapid onset sunlight-induced urticaria, but its pathophysiology is not well understood.
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Mashup Score: 10Persistent Esophageal Changes Following Histologic Remission in Eosinophilic Esophagitis. - 4 month(s) ago
Capsule SummaryThis study identifies persistent mucosal gene expression changes in adult and pediatric eosinophilic esophagitis patients during deep histologic remission, suggesting transcriptome changes accompany EoE regardless of treatment and may be related to disease chronicity.
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Preparing Patients for Oral Immunotherapy (PPOINT): International Delphi consensus for procedural preparation and consent - Journal of Allergy and Clinical Immunology https://t.co/aqESp4Xm8U