Enterohemorrhagic E. coli…lots of fibrin thrombi and ischemic type injury

FNA of a pulmonary hamartoma demonstrates a highly distinctive metachromatic matrix, reminiscent of the metachromatic stroma seen in pleomorphic adenomas. The matrix stains a bright magenta on Romanowsky stain; in tumors with a more immature fibromyxoid stroma, tissue fragments exhibit wispy edges that trail away from the center of the tissue fragment. Cells embedded within the metachromatic…

History – These images are from a gastric biopsy of a pigmented lesion. The patient had no history of melanoma. What is your diagnosis? Answer – Blue nevus of gastric oxyntic mucosa. Comment – Blue nevi are quite rare in the gastrointestinal tract mucosa, but here is an example. The immunostain is a ki-67. This case is provided by Dr. Elizabeth Montgomery, Professor of Pathology, and Vice Chair…

What is the grade of this prostate carcinoma? Answer: The image shows adenocarcinoma with Paneth cell-like differentiation. Note tumor cells with bright and eosinophilic cytoplasm. Nuclei are small and nucleoli not always visible. While the tumor is composed of primarily poorly formed glands, a grade should not be assigned because the majority of the patients with this type of cancer have a…

What is the best diagnosis for this small intestinal tumor? This is a small bowel gastrointestinal stromal tumor. The tumor has an appearance that overlaps with that of a smooth muscle tumor, but note that it is less brightly eosinophilic than the muscularis mucosae above it. www.innovativesciencepress.com info@innovativepathologypress.com 1-703-350-4308/703-340-3198

Beautiful gastric well differentiated neuroendocrine (carcinoid) tumor arising in autoimmune atrophic gastritis. The synaptophysin (red) – ki-67 (brown) combo stain is lovely; note the enterochromaffin-like (ECL) cell hyperplasia in the flat mucosa. This tumor is from the gastric body, which lacks oxyntic mucosa (parietal and chief cells). We are running low on the remaining copies of our GI…