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Mashup Score: 6Can We Pick Winners With Causal Human Biology? Vertex Makes the Case - TimmermanReport.com - 23 day(s) ago
Everybody reading this column knows that biopharma is a difficult business. Biology is unfathomably complicated and figuring out how to introduce something into the human body that does more good than harm is a fiendishly difficult challenge. That’s why it’s important to recognize the occasional success. It reminds us what’s possible, and inspires us to… Read More
Source: timmermanreport.comCategories: General Medicine News, General HCPsTweet
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Mashup Score: 5George Yancopoulos, That Rarest Of Species - A Physician-Scientist Still In Charge Of A Pharma - TimmermanReport.com - 1 month(s) ago
Growing up in an academic household (my parents are both professors at Yale Medical School, still engaged, as ever, in dyslexia research), it was perhaps inevitable that, outside of my parents, my first role model was the brilliant President of Yale University, the late Bart Giamatti (you know- Paul’s dad). The elder Giamatti inspired me… Read More
Source: timmermanreport.comCategories: General Medicine News, General HCPsTweet-
Interesting @AndrewE_Dunn @endpts interview with the great George Yancoploulos (see my paean here https://t.co/uEtGM5ErfF ) on AI in R&D (spoiler: accelerating what REGN's already doing integrating geno+pheno, now incl proteomics...) https://t.co/5qu5Och6ZO @jgreid @TempusAI
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Mashup Score: 9
The two broad categories of medical discovery that command the most attention are insights resulting from rare, informative genetic conditions (see here) and advances resulting from fortuitous observations. A canonical example of the value of extreme genetic phenotypes is the patient with familial hypercholesterolemia who inspired Brown and Goldstein’s scientific pursuit of cholesterol metabolism and… Read More
Source: timmermanreport.comCategories: General Medicine News, General HCPsTweet-
Very exciting though also important to note GLP-1 progress largely not consequence of genetics but 30y roll-up-your-sleeves lab work, as @DanielJDrucker has emphasized-see: https://t.co/jFYv5y7MuZ From obesity Rx POV, genetics mostly disappointing @timmermanreport @matthewherper https://t.co/N6ZZKU6Fck
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Mashup Score: 0
“It’s been a busy few weeks for product announcements in the world of fitness,” industry observer Anthony Vennare recently commented, citing the latest offerings from the Peloton, Mirror, Tempo, and other digital fitness platforms. On the one hand, these developments are encouraging, offering customers pursuing fitness — and who are willing and able to afford… Read More
Source: timmermanreport.comCategories: General Medicine News, General HCPsTweet-
In 2021 I wrote about the value of even a modicum of activity: https://t.co/L9M1LnavTX … @willahmed @onepeloton https://t.co/8BaOibGGVr
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Mashup Score: 3A Story of Hope For Kids With Rare Disease - TimmermanReport.com - 3 month(s) ago
As we head into Thanksgiving, I wanted to share a story that highlights the promise and possibility that can emerge from a devastating diagnosis, and emphasizes what can happen when industry, academia, and — especially — impassioned parents and advocates join forces. Consider the devasting rare genetic disease, spinal muscular atrophy, or SMA. According to… Read More
Source: timmermanreport.comCategories: General Medicine News, General HCPsTweet-
Just up at @timmermanreport - latest column celebrating a rare disease success story in SMA: https://t.co/2OwHMBcsz5 cc @smafoundation @zakkohane @adamjshay
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Mashup Score: 3A Story of Hope For Kids With Rare Disease - TimmermanReport.com - 3 month(s) ago
As we head into Thanksgiving, I wanted to share a story that highlights the promise and possibility that can emerge from a devastating diagnosis, and emphasizes what can happen when industry, academia, and — especially — impassioned parents and advocates join forces. Consider the devasting rare genetic disease, spinal muscular atrophy, or SMA. According to… Read More
Source: timmermanreport.comCategories: General Medicine News, General HCPsTweet-
Just up at @timmermanreport - latest column celebrating a rare disease success story in SMA: https://t.co/2OwHMBcsz5 cc @smafoundation @zakkohane @adamjshay
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Mashup Score: 4Coastal Culture Clash Around AI in Biotech - TimmermanReport.com - 3 month(s) ago
“Does the crowd understand? Is it East versus West Or man against man? Can any nation stand alone?” Burning Heart, by Survivor – Rocky IV In national politics, the culture wars may pit the coasts against the rest of the country. In biotech, however, the AI culture war seems to pit the coasts against each… Read More
Source: timmermanreport.comCategories: General Medicine News, General HCPsTweet-
I write about the coastal culture class in AI+biotech in my latest @timmermanreport , h/t @Chandanananana @LifeSciVC and the glorious 1980s. https://t.co/q8Cu2bYiQu cc @adamjshay @zakkohane @ScottGottliebMD @VentureValkyrie
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Mashup Score: 2Third Rock-backed Trace Neuroscience Debuts with $101M, RNA Drug for ALS - TimmermanReport.com - 3 month(s) ago
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Source: timmermanreport.comCategories: General Medicine News, General HCPsTweet-
Poignant as well as characteristically thoughtful coverage of launch of newco Trace Neuroscience (targeting ALS) by @ldtimmerman @timmermanreport , who lost his grandmother to this horrible disease: https://t.co/YNUbXfZFV1 - ~all top-tier early stage LS VCs seem represented
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Mashup Score: 5And Just Like That: What the Viral Adoption of a Clinical AI App Means for Pharma R&D - TimmermanReport.com - 4 month(s) ago
In 2011, we were experiencing the ascension of technologies like the cloud and the smartphone. Apps had become a thing: social network apps like Instagram (the iPhone “App of the Year” in 2011) and Twitter, utility apps like Evernote and Dropbox, navigation apps like Google Maps and Waze, and game apps like Angry Birds. Yet… Read More
Source: timmermanreport.comCategories: General Medicine News, General HCPsTweet-
In latest @timmermanreport, I describe AI chasm in pharma R&D, the deep skepticism towards AI among seasoned R&D scientists, & how rapid adoption of clinical AI platform @EvidenceOpen shows how fast things can change https://t.co/e5vsxZgIRm @zakkohane @emollick @ScottGottliebMD
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Mashup Score: 5And Just Like That: What the Viral Adoption of a Clinical AI App Means for Pharma R&D - TimmermanReport.com - 4 month(s) ago
In 2011, we were experiencing the ascension of technologies like the cloud and the smartphone. Apps had become a thing: social network apps like Instagram (the iPhone “App of the Year” in 2011) and Twitter, utility apps like Evernote and Dropbox, navigation apps like Google Maps and Waze, and game apps like Angry Birds. Yet… Read More
Source: timmermanreport.comCategories: General Medicine News, General HCPsTweet-
In latest @timmermanreport, I describe AI chasm in pharma R&D, the deep skepticism towards AI among seasoned R&D scientists, & how rapid adoption of clinical AI platform @EvidenceOpen shows how fast things can change https://t.co/e5vsxZgIRm @zakkohane @emollick @ScottGottliebMD
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In her wonderful bk on complexity, @MelMitchell1 points out that even complexity experts can't seem to agree on what exactly the term means. I wonder if same is true for biopharma R&D leaders who now all seem to invoke "human causal biology"... https://t.co/Aep2ABbyrz @zakkohane