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Mashup Score: 0Risk factors for poorer respiratory outcomes in adolescents and young adults born preterm - 2 year(s) ago
Rationale The respiratory outcomes for adult survivors of preterm birth in the postsurfactant era are wide-ranging with prognostic factors, especially those encountered after the neonatal period, poorly understood. Objectives To obtain comprehensive ‘peak’ lung health data from survivors of very preterm birth and identify neonatal and life-course risk factors for poorer respiratory outcomes in…
Source: ThoraxCategories: Latest Headlines, PulmonologyTweet
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Mashup Score: 1
Background Testing is critical for detecting SARS-CoV-2 infection, but the best sampling method remains unclear. Objectives To determine whether nasopharyngeal swab (NPS), oropharyngeal swab (OPS) or saliva specimen collection has the highest detection rate for SARS-CoV-2 molecular testing. Methods We conducted a randomised clinical trial at two COVID-19 outpatient test centres where NPS, OPS…
Source: ThoraxCategories: Latest Headlines, PulmonologyTweet-
Higher SARS-CoV-2 detection of oropharyngeal compared with nasopharyngeal or saliva specimen for molecular testing: a multicentre randomised comparative accuracy study https://t.co/JZQCXMmLGz @TTodsen https://t.co/YqzvaqnLTX
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Mashup Score: 0MUC5B, telomere length and longitudinal quantitative interstitial lung changes: the MESA Lung Study - 2 year(s) ago
Background The MUC5B promoter variant (rs35705950) and telomere length are linked to pulmonary fibrosis and CT-based qualitative assessments of interstitial abnormalities, but their associations with longitudinal quantitative changes of the lung interstitium among community-dwelling adults are unknown. Methods We used data from participants in the Multi-Ethnic Study of Atherosclerosis with…
Source: ThoraxCategories: Latest Headlines, PulmonologyTweet-
MUC5B, telomere length and longitudinal quantitative interstitial lung changes: the MESA Lung Study https://t.co/1HO350reWG @jskim8223 @drdayjee @AnnaPodolanczuk https://t.co/4Ylyoz7rL0
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Mashup Score: 0
Background Lung cancer surgery is associated with a high incidence of postoperative pulmonary complications (PPCs). We evaluated whether enhanced recovery after surgery plus pulmonary rehabilitation was superior over enhanced recovery after surgery alone in reducing the incidence of postoperative PPCs and length of hospital stay. Methods In this pragmatic multicentre, randomised controlled,…
Source: ThoraxCategories: Latest Headlines, PulmonologyTweet-
Adding pulmonary rehabilitation to enhanced recovery after lung cancer surgery appears to be effective in reducing the incidence of postoperative pulmonary complications. https://t.co/tG5RU7MHvo https://t.co/0utUOXO13C
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Mashup Score: 0COPD in Africa: risk factors, hospitalisation, readmission and associated outcomes—a systematic review and meta-analysis - 2 year(s) ago
Background This review aims to synthesise available evidence on the prevalence of chronic obstructive pulmonary disease (COPD), associated risk factors, hospitalisations and COPD readmissions in Africa. Method Using the Met-Analyses and Systematic Reviews of Observational Studies guideline, electronic databases were searched from inception to 1 October 2021. The quality of studies was assessed…
Source: ThoraxCategories: Latest Headlines, PulmonologyTweet-
Respiratory epidemiology COPD in Africa: risk factors, hospitalisation, readmission and associated outcomes—a systematic review and meta-analysis https://t.co/n8nuUKWrIp @chidi_sr @ProfHurst https://t.co/peS58Y11lo
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Mashup Score: 3The relationship between interstitial lung abnormalities, mortality, and multimorbidity: a cohort study - 2 year(s) ago
Background Interstitial lung abnormalities (ILAs) are associated with increased mortality. It is unclear whether multimorbidity accounts for the mortality association or how strongly ILA is associated with mortality relative to other common age-associated diseases. We determined the association of ILA with all-cause mortality adjusted for multimorbidity, compared mortality associated with ILA and…
Source: ThoraxCategories: Latest Headlines, PulmonologyTweet-
The relationship between interstitial lung abnormalities, mortality, and multimorbidity: a cohort study https://t.co/WsfpuR82Ke https://t.co/AnEYdB2TZ9
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Mashup Score: 2Diagnosis and treatment outcomes from prebronchodilator spirometry performed alongside lung cancer screening in a Lung Health Check programme - 2 year(s) ago
Introduction Incorporating spirometry into low-dose CT (LDCT) screening for lung cancer may help identify people with undiagnosed chronic obstructive pulmonary disease (COPD), although the downstream impacts are not well described. Methods Participants attending a Lung Health Check (LHC) as part of the Yorkshire Lung Screening Trial were offered spirometry alongside LDCT screening. Results were…
Source: ThoraxCategories: Latest Headlines, PulmonologyTweet-
Diagnosis and treatment outcomes from prebronchodilator spirometry performed alongside lung cancer screening in a Lung Health Check programme https://t.co/YAhnkLpzif @DrPhilCrosbie https://t.co/Ye3Jpdvfty
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Mashup Score: 1Faster lung function decline in people living with HIV despite adequate treatment: a longitudinal matched cohort study - 2 year(s) ago
Introduction Chronic lung disease is common among people living with HIV (PLWH). We hypothesised that PLWH receiving antiretroviral therapy (ART) have faster lung function decline than matched controls. Methods We performed a prospective matched cohort study by including ART-treated PLWH from the Copenhagen Co-morbidity in HIV Infection Study (n=705) and the INSIGHT Strategic Timing of…
Source: ThoraxCategories: Latest Headlines, PulmonologyTweet-
Faster lung function decline in people living with HIV despite adequate treatment: a longitudinal matched cohort study. https://t.co/KHVMue95ka https://t.co/cL7fIYh1mO
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Mashup Score: 1Cluster analysis of transcriptomic datasets to identify endotypes of idiopathic pulmonary fibrosis - 2 year(s) ago
Background Considerable clinical heterogeneity in idiopathic pulmonary fibrosis (IPF) suggests the existence of multiple disease endotypes. Identifying these endotypes would improve our understanding of the pathogenesis of IPF and could allow for a biomarker-driven personalised medicine approach. We aimed to identify clinically distinct groups of patients with IPF that could represent distinct…
Source: ThoraxCategories: Latest Headlines, PulmonologyTweet-
Cluster analysis of transcriptomic datasets to identify endotypes of idiopathic pulmonary fibrosis https://t.co/76v9Uqgh7G @KravenLuke https://t.co/RITJKBKsIn
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Mashup Score: 0Patient perspectives on the use of indwelling pleural catheters in malignant pleural effusions - 2 year(s) ago
Background Indwelling pleural catheters are an effective treatment option for patients with malignant pleural effusions. Despite their popularity, there remains a paucity of data on the patient experience and key patient-centred outcomes. Objective To investigate the experience of patients receiving an indwelling pleural catheter to better inform and identify potential areas for improvement in…
Source: ThoraxCategories: Latest Headlines, PulmonologyTweet-
Patient perspectives on the use of indwelling pleural catheters in malignant pleural effusions https://t.co/maKKsClemW https://t.co/cCUaCONyN3
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Risk factors for poorer respiratory outcomes in adolescents and young adults born preterm https://t.co/9dVDmZcZWr @DrLizFSmith https://t.co/9dLhw3tDGS