• Mashup Score: 8

    Multiple retinal diseases can manifest with similar phenotypical findings. The so-called “bullseye maculopathy” is a classic finding for conditions that affect the central macula. The dark center of the fovea is surrounded by a lighter ring, indicating disease-related changes. The differential diagnosis includes a variety of inherited and acquired conditions, such as cone-rod dystrophies,…

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    • Editorial: Macular Telangiectasia Type 2 versus Tamoxifen Retinopathy: How to Hit a Diagnostic Bullseye https://t.co/WfN7HrbzIJ #ophthalmology #retina https://t.co/OE081nneWf

  • Mashup Score: 6

    A broad spectrum of autosomal dominant inherited retinal diseases (IRDs), including both mild macular pattern dystrophies and severe cone-rod degenerations, is associated with PRPH2 variants (“peripherinopathies”). We present a detailed clinical and molecular characterization of patients affected by peripherinopathies, aiming to expand the mutational spectrum and propose novel genotype-phenotype…

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    • In this retrospective study, the authors provide a detailed clinical and molecular characterization of inherited retinal diseases associated with PRPH2 variants, expanding the mutational spectrum, and proposing genotype-phenotype correlations. https://t.co/3hA211tOKl https://t.co/saf0Qt5D1S

  • Mashup Score: 4

    A 45-year-old man presented with decreased vision in the right eye. Relevant medical history included familial hypertriglyceridemia, kidney transplantation, sensorineural hearing loss, and diabetes. Fundoscopy revealed yellowish petaloid-shaped intraretinal deposits, along with vessel attenuation and bone spicule hyperpigmentation in the midperiphery (Fig A). On spectral-domain–OCT, cystoid…

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    • “Lipoid” Macular Edema in Familial Hypertriglyceridemia and Retinal Dystrophy https://t.co/IGE4Rv9tCd https://t.co/do5bJ6PPTX

  • Mashup Score: 0

    Geographic atrophy (GA), the advanced form of nonexudative age-related macular degeneration (atrophic AMD, aAMD), is a major cause of central visual loss in people aged > 60 years. Geographic atrophy currently has no treatment; however, there are > 10 clinical trials (clinicaltrials.gov, October 6, 2022), 2 with promising results in Phase III.

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    • In the coding of nonexudative age-related macular degeneration, geographic atrophy is under-reported by retina specialists. https://t.co/nVY6onUSy8 https://t.co/fCAQJAjFGb