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Mashup Score: 0100 years of glucagon: Anniversary collection - 12 month(s) ago
The year 2023 marks 100 years since publication of the first report of a hyperglycemic factor in pancreatic extracts which CP Kimball and John R Murlin named glucagon (from GLUCose AGONist). Glucagon has a range of profound effects on metabolism including, but not limited to its effect stimulate hepatic glucose production. Its dysregulation plays an important role in the pathogenesis of…
Source: joeCategories: Endocrinology, Latest HeadlinesTweet
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Mashup Score: 1Endocrine Society of Australia Special Collection - 12 month(s) ago
In collaboration with the Endocrine Society of Australia, and led by Guest Editors Professor Bu Yeap and Professor Tim Cole, Journal of Endocrinology (JOE) has invited this collection of articles from some of the region’s leading Endocrine researchers. Collection Guest Editors: Professor Timothy Cole, Guest Editor Professor of Biochemistry & Molecular…
Source: joeCategories: Endocrinology, Latest HeadlinesTweet-
Explore the first six articles published in our Special Collection in collaboration with the Endocrine Society of Australia (@EndoSocAus), curated by Professor Timothy Cole (@MonashBDI) and Professor Bu Yeap (@UWAresearch): https://t.co/7K91UPh7Hf https://t.co/ceMNSL4GMo
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Mashup Score: 0NLRP3 inflammasome activation, metabolic danger signals, and protein binding partners - 1 year(s) ago
The NOD-like receptor family pyrin domain-containing 3 (NLRP3) inflammasome is an oligomeric complex that assembles in response to exogenous signals of pathogen infection and endogenous danger signals of non-microbial origin. When NLRP3 inflammasome assembly activates caspase-1, it promotes the maturation and release of the inflammatory cytokines interleukin-1B and IL-18. Aberrant activation of…
Source: joeCategories: Endocrinology, Latest HeadlinesTweet-
Sy-Ying Leu (@NCKU_official) et al. present the mechanisms underlying NLRP3 inflammasome activation after induction by metabolic danger signals or via protein–protein interactions with NLRP3 that likely occur in metabolic diseases. Read the full review: https://t.co/Pw0orAPed0 https://t.co/RxaxkMmp3h
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Mashup Score: 0Fructose drives de novo lipogenesis affecting metabolic health - 1 year(s) ago
Despite the existence of numerous studies supporting a pathological link between fructose consumption and the development of the metabolic syndrome and its sequelae, such as non-alcoholic fatty liver disease (NAFLD), this link remains a contentious issue. With this article, we shed a light on the impact of sugar/fructose intake on hepatic de novo lipogenesis (DNL), an outcome parameter known to…
Source: joeCategories: Endocrinology, Latest HeadlinesTweet-
Bettina Geidl-Flueck & Philipp A Gerber (@Unispital_USZ @UZH_en) show the impact of fructose intake on hepatic de novo lipogenesis, an outcome parameter known to be dysregulated in subjects with type 2 diabetes and/or non-alcoholic fatty liver disease. https://t.co/otxH3f5hmM https://t.co/jqVbbqVJAQ
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Mashup Score: 0Editorial Board - 1 year(s) ago
Joint JOE and JME international editorial board
Source: joeCategories: Endocrinology, Latest HeadlinesTweet-
The Journal of Endocrinology's editorial board has over 25 internationally renowned and geographically diverse editors in place to oversee the peer-review process. Take a look at each of our Editor's research interests: https://t.co/oTe99vhNlI https://t.co/rXNfrytKd4
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Mashup Score: 0The physiology of growth hormone (GH) in adults: translational journey to GH replacement therapy - 1 year(s) ago
The fact that growth hormone (GH) plays an important role in health after the cessation of growth requiring replacement therapy in adult life has only been recognised in the last three decades. This has only been made possible by recombinant technology providing GH supplies required to undertake investigations in the physiology of GH action and the benefits of replacement therapy in patients…
Source: joeCategories: Endocrinology, Latest HeadlinesTweet-
Read this review by Ken KY Ho, Anthony J O’Sullivan, and Morton G Burt 'The physiology of growth hormone (GH) in adults: translational journey to GH replacement therapy' - part of our Special Collection produced in collaboration with the @EndoSocAus https://t.co/4NUR7ZbUbZ https://t.co/9AuaLfU5y9
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Mashup Score: 0
There is longstanding interest in the role of androgens in the aetiology of prostate cancer, one of the most common malignancies worldwide. In this review, we reflect on the ways that knowledge of prostate development and hormone action have catalysed advances in the management of patients with prostate cancer. The use of hormone therapies to treat prostate cancer has changed significantly over…
Source: joeCategories: Endocrinology, Latest HeadlinesTweet-
Read this review by @ReneaTaylor1 et al. (@MonashBDI @UniMelb @PeterMacCC) reflecting on the ways that knowledge of prostate development and hormone action have catalysed advances in the management of patients with prostate cancer. https://t.co/ASgyGajoFX https://t.co/iA6Xmi92Fu
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Mashup Score: 1Hypothyroidism induces motor deficit via altered cerebellar HB-EGF/EGFR and autophagy - 1 year(s) ago
Thyroid hormones (TH) are vital for brain functions, while TH deficiency, i.e. hypothyroidism, induces neurological impairment in children and adults. Cerebellar neuronal apoptosis and motor deficits are crucial events in hypothyroidism; however, the underlying mechanism is less-known. Using a methimazole-treated hypothyroidism rat model, we investigated cerebellar autophagy, growth factor, and…
Source: joeCategories: Endocrinology, Latest HeadlinesTweet-
Read this recent research 'Hypothyroidism induces motor deficit via altered cerebellar HB-EGF/EGFR and autophagy' by Jitendra Vishwakarma et al. (@AcSIR_India, @CSIR_IITR) https://t.co/hYnY3wp0J9 https://t.co/dN6yrgnvTw
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Mashup Score: 0Alerts - 1 year(s) ago
Sign up to receive journal email newsletters, containing the latest news and content. You can unsubscribe at any time. Content alerts To create a content alert, including table of contents updates, accepted manuscript alerts and RSS feeds, please click “Create Account” and follow the steps to create a free account. Add alerts by going to the ‘Content’ tab, ‘All issues’ page and…
Source: joeCategories: Endocrinology, Latest HeadlinesTweet-
Make finding research relevant to your work even easier. Sign up to receive the latest published articles direct to your inbox! https://t.co/0iy66qwv5G #Endocrinology https://t.co/Pl4rVkopff
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Mashup Score: 0
There are many previous reports on the effects of ethanol on physiological function, including reports of elevated blood estrogen levels in women who drank alcohol. However, the mechanism of ethanol’s effects on ovarian functions, such as follicle development and hormone secretion, has not been fully clarified. Therefore, in this study, we investigated the impacts of ethanol on these phenomena…
Source: joeCategories: Endocrinology, Latest HeadlinesTweet-
Recent research by Yuta Kasahara et al. shows ethanol potentiates follicle-stimulating hormone action in ovarian granulosa cells suggesting alcohol intake is an exacerbating factor in some female hormone-related diseases. Read more: https://t.co/VFaUp3ikMf https://t.co/eh94COQpIf
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Check out the first articles published in our Special Collection marking 100 years since the discovery of Glucgaon, curated by Editors James Cantley, @RebeccaLHull and Vincent Poitout (@VPoitout): https://t.co/TL8xJ9bYbj https://t.co/zSVBorFKuM