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Mashup Score: 0Antiplatelet Effects of Clopidogrel Vs Aspirin in Virologically Controlled HIV: A Randomized Controlled Trial - 1 year(s) ago
Highlights • In treated HIV, cardiovascular disease is a leading cause of morbidity and mortality, the prevention of which is not fully known. • Activated platelets are causal in atherosclerotic ca…
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Mashup Score: 6Determinants of Endogenous Fibrinolysis in Whole Blood Under High Shear in Patients With Myocardial Infarction: - 1 year(s) ago
Highlights • Hypofibrinolysis is a recently-recognized risk factor for recurrent cardiovascular events in patients with STEMI, but its mechanistic determinants are not well understood. • In patient…
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Mashup Score: 0LncRNA-ZFAS1 Promotes Myocardial Ischemia-Reperfusion Injury Through DNA Methylation-Mediated Notch1 Down-Regulation in Mice: - 1 year(s) ago
Highlights • The increase of ZFAS1 expression in MIRI is an important cause of cardiomyocyte apoptosis and ROS production. • ZFAS1 can directly interact with the promoter region of Notch1, recruit …
Categories: Cardiac Surgery, Latest HeadlinesTweet
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Mashup Score: 2Plasminogen Activator Inhibitor-1–Positive Platelet-Derived Extracellular Vesicles Predicts MACE and the Proinflammatory SMC Phenotype: - 1 year(s) ago
Highlights • This study shows the existence of PAI-1+ PEVs. Approximately 20% of plasma PAI-1 is composed of PAI-1+ PEVs. • Elevated PAI-1+ PEV levels were predictive of 1-year major adverse cardia…
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Mashup Score: 0A Novel LncRNA SNHG3 Promotes Osteoblast Differentiation Through BMP2 Upregulation in Aortic Valve Calcification: - 1 year(s) ago
Highlights • The long noncoding RNA SNHG3 was upregulated in the leaflets of both patients and mice with calcific aortic valve disease. • SNHG3 can associate with EZH2 in the nucleus of hVICs to ep…
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Mashup Score: 2TNFR1 Contributes to Activation-Induced Cell Death of Pathological CD4+ T Lymphocytes During Ischemic Heart Failure: - 1 year(s) ago
Highlights • CD4+ T lymphocytes exhibit a temporal phenotypic shift associated with increased TNF-α expression during ischemic heart failure. Importantly, TNF-α expression is highest in TNFR1+ vers…
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Mashup Score: 7Translating Imaging Into 3D Printed Cardiovascular Phantoms: A Systematic Review of Applications, Technologies, and Validation - 2 year(s) ago
Highlights • 3D printed patient specific phantoms can visualize complex cardiovascular anatomy • Common imaging modalities for 3D printing are CCT and CMR • Material jetting/PolyJet and stereolitho…
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Mashup Score: 3Distinct Mechanisms for Increased Cardiac Contraction Through Selective Alteration of Either Myosin or Troponin Activity: - 2 year(s) ago
Highlights • Myosin-based thick filament (CK-138 or M) and troponin-based thin filament (CK-030 or T) selective compounds improved cardiac muscle contraction and calcium sensitivity • T exhibited f…
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Mashup Score: 3
Highlights • Human cardiac slices cultured with SB216763 showed reduced conduction velocity and decreased excitability, as measured by dVm/dtmax, at 3 and 24 hours compared to slices cultured in co…
Categories: Cardiologists, Latest HeadlinesTweet
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Mashup Score: 2
Highlights • Human cardiac slices cultured with SB216763 showed reduced conduction velocity and decreased excitability, as measured by dVm/dtmax, at 3 and 24 hours compared to slices cultured in co…
Categories: Cardiac Surgery, Latest HeadlinesTweet
Does #clopidogrel offer beneficial antiplatelet properties in #HIV patients? Learn more in #JACCBTS: https://t.co/YxfdZcomYx #Aspirin #openaccess #BasicResearch #TranslationalResearch #CardioTwitter @plateletdoc https://t.co/bA1y5ElXI3