• Mashup Score: 5

    Background: Age-specific differences in the concentration and function of several haemostatic proteins have been investigated previously and are encompassed under the concept of Developmental Haemostasis.  However, few studies have investigated the effect of age and development on von Willebrand Factor (vWF) and its multimers. This is critical for accurate diagnosis and management of neonates and…

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    • Pediatric coagulation reference ranges are always challenging given the evolution of the system over time. This #isth2021 abstract from Letunica and colleagues evaluates age-specific changes in von Willebrand factor multimers in healthy children and adults https://t.co/c9UKmdfXX2

  • Mashup Score: 0

    Background: Qualitative or quantitative defects of Von Willebrand Factor (VWF) such as in Von Willebrand Disease (VWD) are associated with vascular abnormalities, especially in the gastrointestinal (GI) tract. However, the locations, extent, and natural history of these abnormalities in patients with VWD is not well understood. Aims: In order to summarise the existing literature on […]

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    • #ISTH2021 Abstract summarizing literature on vascular abnormalities in patients with #VWD: Vascular Abnormalities in Patients with Von Willebrand Disease: A Scoping Review https://t.co/Tvqy7FQBcJ