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    The P-value remains a widely used statistical concept in medicine. Ubiquitous in clinical trial reports, we have relied heavily on this tool to highlight results more worthy of attention. However, there has been longstanding concern that a lack of nuanced understanding of the scope and interpretation of P-values could lead to inappropriate conclusions [1–4]. This is not only a problem for…

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    The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

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