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Mashup Score: 10SOHO State of the Art Updates and Next Questions: Novel Therapies in Development for Myelofibrosis - 1 year(s) ago
Myeloproliferative neoplasms research has entered a dynamic and exciting era as we witness exponential growth of novel agents in advanced/early phase clinical trials for myelofibrosis (MF). Building on the success and pivotal role of ruxolitinib, many novel agents, spanning a wide range of mechanisms/targets (epigenetic regulation, apoptotic/intracellular signaling pathways, telomerase, bone…
Categories: Hem/Oncs, Latest HeadlinesTweet
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Mashup Score: 2
Micro-AbstractHyperfractionated cyclophosphamide-dexamethasone (hyperCd) with or without carfilzomib and/or daratumumab is a potential treatment option for patients with multiple myeloma needing rapid disease control. This retrospective analysis of 97 patients describes the safety and efficacy of these regimens. With hyperCd-based therapy, rapid disease control is achievable. Associated…
Categories: Hem/Oncs, Latest HeadlinesTweet-
Hyperfractionated Cytoxan-based Rx for rel/ref MM. N=97, median 5 prior lines of Rx. ORR: 71.8%, median PFS: 4.3 months, median OS: 9.0 months @DrKrinaPatel @Myeloma_Doc @MDAndersonNews #mmsm https://t.co/KP1g2SmYG5
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Mashup Score: 0Rates of Influenza and Pneumococcal Vaccination and Correlation With Survival in Multiple Myeloma Patients - 1 year(s) ago
MicroabstractWe analyzed vaccination rates and associated outcomes of patients with multiple myelom in the INSIGHT MM study. Influenza vaccination in the prior 2 years and pneumococcal vaccination in the prior 5 years impacted overall survival versus no vaccination. Additionally, deaths due to infections were lower among vaccinated versus non-vaccinated patients. Vaccination status should be…
Categories: Hem/Oncs, Latest HeadlinesTweet-
Rates of Influenza and Pneumococcal Vaccination and Correlation with Survival in Multiple Myeloma Patients [Dec 6, 2022] @mtmdphd et al. @AjaiChari CLML https://t.co/kUQeRmeiMt #NCT02761187 #mmsm #IDonc #ClinicalTrials #caxtx https://t.co/ylV87voRLL
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Mashup Score: 2Vaccination in Multiple Myeloma: Review of Current Literature - 1 year(s) ago
Multiple myeloma is a cancer of the immune system. Infection is a major cause of morbidity and mortality in patients with multiple myeloma. Some of these infections are preventable by vaccines available to the general population. However, little is known about the clinical effectiveness of these vaccines in patients with multiple myeloma, and the cellular and humoral immune response to…
Categories: Hem/Oncs, Latest HeadlinesTweet-
Vaccination in Multiple Myeloma: Review of Current Literature [Jun 8, 2016] Alemu et al. @mtmdphd CLML https://t.co/bhwKr0obt4 #mmsm #ImmunoOnc #IDonc https://t.co/Gs34MFRfz6
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Mashup Score: 1Rates of Influenza and Pneumococcal Vaccination and Correlation With Survival in Multiple Myeloma Patients - 1 year(s) ago
MicroabstractWe analyzed vaccination rates and associated outcomes of patients with multiple myelom in the INSIGHT MM study. Influenza vaccination in the prior 2 years and pneumococcal vaccination in the prior 5 years impacted overall survival versus no vaccination. Additionally, deaths due to infections were lower among vaccinated versus non-vaccinated patients. Vaccination status should be…
Categories: Hem/Oncs, Latest HeadlinesTweet-
Rates of Influenza and Pneumococcal Vaccination and Correlation with Survival in Multiple Myeloma Patients [Dec 6, 2022] @mtmdphd et al. @AjaiChari CLML https://t.co/kUQeRmeiMt #NCT02761187 #mmsm #IDonc #ClinicalTrials #caxtx https://t.co/D5CsXxUQRK
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Mashup Score: 1Rates of Influenza and Pneumococcal Vaccination and Correlation With Survival in Multiple Myeloma Patients - 1 year(s) ago
MicroabstractWe analyzed vaccination rates and associated outcomes of patients with multiple myelom in the INSIGHT MM study. Influenza vaccination in the prior 2 years and pneumococcal vaccination in the prior 5 years impacted overall survival versus no vaccination. Additionally, deaths due to infections were lower among vaccinated versus non-vaccinated patients. Vaccination status should be…
Categories: Hem/Oncs, Latest HeadlinesTweet-
Rates of Influenza and Pneumococcal Vaccination and Correlation with Survival in Multiple Myeloma Patients [Dec 6, 2022] @mtmdphd et al. @AjaiChari CLML https://t.co/kUQeRmeiMt #NCT02761187 #mmsm #IDonc #ClinicalTrials #caxtx https://t.co/s1Te6DXlhr
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Mashup Score: 2State of the Art Updates and Next Questions: Treatment of Lower Risk Myelodysplastic Syndromes - 1 year(s) ago
MDS is a clonal stem cell neoplasm with a spectrum from lower risk disease to short term life threatening higher risk disease. The disease risk is dictated by clinical and molecular features. Majority of MDS patients including lower risk disease unfortunately succumb from disease related complications namely cytopenia. While cytopenias may be mild early upon diagnosis and can be surveilled,…
Categories: Hem/Oncs, Latest HeadlinesTweet-
Our latest manuscript State of the Art Updates and Next Questions: Treatment of Lower Risk Myelodysplastic Syndromes, great summary by @Volpe_MD and collaborating with @garciamanero https://t.co/JrzD5OiOXp @MoffittNews @MoffittHemOnc
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Mashup Score: 1Rates of Influenza and Pneumococcal Vaccination and Correlation With Survival in Multiple Myeloma Patients - 1 year(s) ago
MicroabstractWe analyzed vaccination rates and associated outcomes of patients with multiple myelom in the INSIGHT MM study. Influenza vaccination in the prior 2 years and pneumococcal vaccination in the prior 5 years impacted overall survival versus no vaccination. Additionally, deaths due to infections were lower among vaccinated versus non-vaccinated patients. Vaccination status should be…
Categories: Hem/Oncs, Latest HeadlinesTweet-
Rates of Influenza and Pneumococcal Vaccination and Correlation with Survival in Multiple Myeloma Patients [Dec 6, 2022] @mtmdphd et al. @AjaiChari CLML https://t.co/kUQeRmeiMt #NCT02761187 #mmsm #IDonc #ClinicalTrials #caxtx https://t.co/IsQrth0H8s
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Mashup Score: 1
We conducted a systematic review and meta-analysis to compare outcomes of tyrosine kinase inhibitor (TKI) maintenance therapy with or without allogeneic hematopoietic stem cell transplantation (HSCT) in Philadelphia chromosome-positive (Ph+) acute lymphoblastic leukemia (ALL) in first remission (CR1). A literature search was performed on PubMed, Cochrane, and Clinical trials.gov. After screening…
Categories: Hem/Oncs, Latest HeadlinesTweet-
Outcomes of Tyrosine Kinase Inhibitors Maintenance Therapy with or without Allogeneic Hematopoietic Stem Cell Transplantation in Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia in First Complete Remission https://t.co/S0jHHKHYGU
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Mashup Score: 1
Relapsed/refractory central nervous system (CNS) lymphoma, whether primary or secondary, is associated with poor prognosis with currently available treatment modalities, including high-dose chemotherapy-autologous stem cell transplantation. The pivotal ZUMA-1 and JULIET trials that led to FDA approval of Axicabtagene ciloleucel and Tisagenlecleucel for relapsed refractory large cell lymphoma…
Categories: Hem/Oncs, Latest HeadlinesTweet-
Chimeric Antigen Receptor T-Cell (CAR T-Cell) Therapy for Primary and Secondary Central Nervous System Lymphoma: A Systematic Review of Literature #lymsm https://t.co/W6aL9X5QCX
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Nice talk today by our own Dr Serge Verstovsek “Dr V” on MPN overview and review @MDAndersonNews Grand Rounds this am highlighting future novel pathways beyond JAK inhibition on this slide based on our group’s review article together | https://t.co/8iCnjzMDnv | #MPNSM https://t.co/NtIjSSt2Mb