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Mashup Score: 21Studies of an experimental ovarian cancer therapy identify a biomarker of treatment response - 2 month(s) ago
A new biomarker may identify patients who can benefit from drugs that inhibit CHK1 after their ovarian cancer has become resistant to PARP inhibitors.
Source: ccr.cancer.govCategories: General Medicine News, Onc News and JournalsTweet
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Mashup Score: 25Genomic Classification of Tumors - 3 month(s) ago
While it is current practice today to molecularly characterize tumors based on their genetic fingerprints, CCR investigators were among the first to classify tumors based on genetics. As a result, treatments are now being tailored to an individual’s specific cancer subtype, and new therapies are being developed to target the vulnerabilities of different types of cancer cells. Major CCR successes in this area have improved the classification of kidney cancers and lymphomas and have laid the foundation for what is now called precision medicine.
Source: ccr.cancer.govCategories: General Medicine News, Oncologists1Tweet-
Some people with cancer have their tumors analyzed for molecular characteristics that could help inform treatment. NCI Center for Cancer Research investigators were among the first to classify tumors based on #genetics, as this overview explains. https://t.co/f90FNnfuig https://t.co/5Ucp05nJ2L
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Mashup Score: 44
A new machine learning algorithm can dig deep into spectral data of brain tumor tissue to reveal genetic mutations, DNA methylation and even the fat content of gliomas. This research advance could help scientists better classify — and one day better treat — brain cancer.
Source: ccr.cancer.govCategories: General Medicine News, Oncologists1Tweet-
A new #AI tool, called APOLLO, can sift through spectral data derived from brain tumor tissue to reveal a wealth of information, including gene activations and mutations, and even which lipid molecules are present in the tumors. Learn more: https://t.co/rEHBCqo6Il https://t.co/8MhmSTb2kN
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Mashup Score: 10Learning from Our Pets | Center for Cancer Research - 3 month(s) ago
Studying osteosarcoma in dogs may improve treatment options for people and pets.
Source: ccr.cancer.govCategories: General Medicine News, Onc News and JournalsTweet-
#Osteosarcoma is an aggressive bone cancer that occurs in dogs and people. New research involving studies of pet dogs with the cancer suggests potential strategies for treating both 4-legged and 2-legged patients. @NCIResearchCtr https://t.co/B6uU0FXxMg #NationalPetDay https://t.co/3gk44JEwMn
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Mashup Score: 20
Waves of regulatory changes can transform self-renewing neuroblastoma cells into neurons.
Source: ccr.cancer.govCategories: General Medicine News, Onc News and JournalsTweet-
Investigators at the @NCIResearchCtr have mapped key regulatory changes that occur when a common neuroblastoma therapy, retinoic acid, drives tumor cells to develop into neurons, thereby curbing their growth. Learn more: https://t.co/dIrURf1Sp5 #BCSM #PediatricCancer
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Mashup Score: 61Fatima Karzai, M.D. - 3 month(s) ago
Dr. Karzai is an internationally recognized physician with expertise in all stages of prostate cancer and clinical trial development. Her clinical research program includes genetics/genomics, imaging, immunotherapy, and health disparities. Dr.
Source: ccr.cancer.govCategories: General Medicine News, Hem/OncsTweet-
📣🎉Congratulations Dr. Fatima Karzai @FatimaKarzai @nciccr_gmb @NCIResearchCtr @theNCI 🎉👏🏼 🔬For more on her #ProstateCancer research program 🧬 https://t.co/6kfDjEYRUD https://t.co/XM49zyUpXI
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Mashup Score: 13
Researchers uncovered the mechanisms behind a drug treatment for diffuse large B-cell lymphoma (DLBCL). The findings help clarify why certain patients respond well to the treatment, while others do not.
Source: ccr.cancer.govCategories: General Medicine News, Oncologists1Tweet-
A new study suggests a promising way to treat people with diffuse large B-cell lymphoma, the most common type of aggressive non-Hodgkin lymphoma. Learn more: https://t.co/sWtJUbUAP3 #DLBCL @NCIResearchCtr https://t.co/n4oIxt1Mk7
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Mashup Score: 32Repairing DNA that breaks during replication - 3 month(s) ago
DNA replication can generate double-strand DNA breaks. CCR scientists clarify how these breaks form and how cells repair the potentially catastrophic damage.
Source: ccr.cancer.govCategories: General Medicine News, Oncologists1Tweet-
What happens when easy-to-repair nicks in a DNA molecule are converted into potentially catastrophic double-strand breaks during the process of DNA replication? Scientists at @NCIResearchCtr answer this question in a new study: https://t.co/5wKbF6CeE1 https://t.co/r8AhuQ4mne
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Mashup Score: 31
CCR researchers have developed the largest publicly accessible sarcoma cell line database called Sarcoma CellMinerCDB. The tool merges previously available and new sarcoma cell line data that can be used to identify new therapeutic targets for these cancers.
Source: ccr.cancer.govCategories: General Medicine News, Oncologists1Tweet-
NCI scientists have developed the largest publicly accessible database of #sarcoma cell line data. Sarcoma CellMinerCDB will help researchers worldwide develop knowledge that could lead to new treatments for the disease. https://t.co/mDG7Kiy8NF #SarcomaAwareness
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Mashup Score: 9Samira M. Sadowski, M.D. - 4 month(s) ago
Dr. Sadowski’s research focuses on the identification of diagnostic and prognostic markers for endocrine tumors and developing new therapies for such tumors. She has extensive experience in the field of endocrine surgery.
Source: ccr.cancer.govCategories: General Medicine News, Hem/OncsTweet-
Congratulations to Dr Sadowski @samira_sadowski who is an alum form the Physician Scientist Early Investigator Program(PEIP) @NCIResearchCtr For more on her research: https://t.co/4oG0bEyf2P For more on the PEIP program https://t.co/86YxGAK1Ji https://t.co/eHb5CjkrlE
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#Studies of an experimental #OvarianCancer therapy identify a potential biomarker of treatment response. https://t.co/L0TPzgxy3H #CancerTreatment @NCIResearchCtr