The sooner macular neovascularization in age-related macular degeneration (AMD) is detected the better the outcomes of treatment.1,2 This is especially significant in second-affected eyes because the patients have so much more to lose.3,4 With serial clinical examination and optical coherence tomography (OCT) scans, clinicians may be able to detect the early onset of active or exudative…

Glaucoma is a slowly progressive optic neuropathy characterized by damage to the retinal ganglion cell axons at the level of the optic nerve head and subsequent loss of retinal ganglion cells across the retina.1 The irreversible nature of damage in glaucoma makes early detection of the disease or its progression essential.2 Optical coherence tomography (OCT) is now considered a standard tool for…

To report the anterior segment clinical features and histopathologic and histochemical characteristics of explanted corneas from the largest reported cohort of patients with Hurler syndrome and other variants of mucopolysaccharidosis (MPS) I undergoing corneal transplantation.

Allergic conjunctivitis, which affects approximately 20%-40% of the population in the United States, is characterized by ocular itching and other symptoms that negatively affect quality of life.1,2 Topical antihistamines are generally considered the standard of care for allergic conjunctivitis, although in an Italian study up to 60% of patients required additional medication, including topical…

To describe the value of integrating phenotype/genotype data, disease staging, and evaluation of functional vision in patient-centered management of retinal dystrophies.