Xconomy: Athira Aims for the Nasdaq to Advance Alzheimer’s Drug to Phase 2 Tests
Many of the drugs tested in Alzheimer’s disease so far, and some still in development, aim to block or break up proteins associated with the progression
Many of the drugs tested in Alzheimer’s disease so far, and some still in development, aim to block or break up proteins associated with the progression
Myeloma Paper of the Day, May 10th, suggested by Robert Orlowski / Alexandre Eeckhoutte, Amina Joudat, Avital Tenenbaum, Brian A Walker, cancer, Damien
We carried out a single-cell (sc) multiomic analysis on a series of MYD88 mutated Waldenström macroglobulinemia (WM) cases and identified two distinct subtypes of disease,…
ClinicalTrials.gov Identifier: NCT04549363.
Myeloma Paper of the Day, May 8th, suggested by Robert Orlowski / Anjan Thakurta, Anshul Thakur, blood advances, cancer, Christopher C Butler, David A
Dysregulated immune proteins in plasma in the UK Biobank predict Multiple Myeloma 12 years before clinical diagnosis
This study focused on the role of plasma cells in multiple myeloma (MM) and the associated potential mechanisms. Transcriptomic data of MM and various gene…
Chimeric antigen receptor (CAR) T cell therapy is effective for multiple myeloma (MM), yet patients with plasmacytomas, either paraskeletal disease (PSD) or extramedullary disease (EMD),…
Cell communication systems based on polypeptide ligands use transmembrane receptors to transmit signals across the plasma membrane. In their biogenesis, receptors depend on the endoplasmic…
CD56 expression modulates NAD+ metabolic landscape and predicts sensitivity to anti-CD38 therapies in multiple myeloma
In addition to advanced age, patients with relapsed refractory multiple myeloma (RRMM) are often frail with pre-existing comorbidities and poor performance status and have been…