Senolytic Therapy in Sleep Apnea: Murky Waters or Fountain of Youth?
A debate continues regarding the chronic health impacts of obstructive sleep apnea (OSA). Central to this debate is how to interpret randomized trials showing lack of cardiovascular benefit from continuous positive airway pressure (CPAP). Several narratives have emerged to comprehend these results, which might be grouped into three schools of thought. First is the possibility that CPAP benefits only certain patients who might be identified by symptoms or polysomnographic features other than the apnea–hypop