Retraction
On 28 April 2006, Science published the Report “Proapoptotic BAX and BAK modulate the unfolded protein response by a direct interaction with IRE1a” by C. Hetz et al. (1). Based on an internal analysis that began in February 2021, the authors have become aware of discrepancies in the controls shown in Figs. 1A and 6A and figs. S2, B and C; 3A; and S5, D to F. The authors are no longer confident that these figures support the conclusions. As a result, the authors are retracting the paper. Author Claudio Hetz disagrees with the decision to retract. Author Stanley J. Korsmeyer is deceased. Authors Bruno Antonsson, Michael C. Bassik, Paula Bernasconi, and Jill Fisher could not be reached.