Quantitative bias analysis for external control arms using real-world data in clinical trials: a primer for clinical researchers
Development of medicines in rare oncologic patient populations are growing, but well-powered randomized controlled trials are typically extremely challenging or unethical to conduct in such settings. External control arms using real-world data are … Plain language summary Doctors and biomedical researchers are working hard to develop new medicines for rare types of cancer, but conducting traditional, strong clinical trials can be very difficult or even wrong in these cases. To help with this, … Tweetable abstract Navigating the complexities of cancer research in rare cases is challenging. Real-world data comparison is a game-changer, but it comes with hurdles. Enter Quantitative Bias Analysis – a tool that helps us understand and correct errors …