Prolonged Opioid Use and Pain Outcome and Associated Factors after Surgery under General Anesthesia: A Prospective Cohort Association Multicenter Study

In these prospectively collected cohort data, preoperative opioid use was identified as the strongest risk factor for opioid use at 3 months postoperatively. No correlation was found between persistent opioid use at 3 months and surgical site pain at 3 months. No association was identified between preoperative anxiety, preoperative depression, or surgery type and opioid use at 3 months in…

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