Progression-free survival, disease-free survival and other composite end points in oncology: improved reporting is needed.pdf

Page 2 of 11Nature Reviews Clinical Oncology Perspective death from any cause, whichever occurs first. Most commonly, progres- sion of solid tumours is determined using the revised Response Evalu- ation Criteria In Solid Tumors (RECIST 1.1) guidelines5 , which define progressive disease as an increase of ≥20% in the sum of diameters of target lesions (maximum of five and two per organ, each >10…

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