Predicting Conversion to Psychosis: What Lies Beyond the Biomarkers?
The challenges of early identification and treatment of individuals with psychotic disorders are substantial. Among the heterogeneous groups of teens identified as being at high risk for psychosis, based on clinical manifestations established by interviews and scales, only about 1 out of 4 individuals actually converts to a chronic psychotic disorder (1). This 75% “false positive” rate reflects both the complex interplay of neurological and psychological development during transitional ages and highlights